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The neuropathology of fatal cerebral malaria in malawian children

The neuropathology of fatal cerebral malaria in malawian children

http://www.wikidata.org/entity/Q34838321

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Cerebral malaria: mysteries at the blood-brain barrier Lethal malaria: Marchiafava and Bignami were right Expanding the antimalarial toolkit: Targeting host-parasite interactions Fighting the Monster: Applying the Host Damage Framework to Human Central Nervous System Infections Endothelial-Leukocyte Interaction in Severe Malaria: Beyond the Brain Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach Endothelin-1 and its role in the pathogenesis of infectious diseases Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis?Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria Microglia development and function Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria Neuroimmunological blood brain barrier opening in experimental cerebral malaria The role of animal models for research on severe malaria Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria Transient lesion in the splenium of the corpus callosum in acute uncomplicated falciparum malaria.Platelet interactions with viruses and parasites.Complement receptor 1 and malaria.Binding of subdomains 1/2 of PfEMP1-DBL1α to heparan sulfate or heparin mediates Plasmodium falciparum rosetting.EPCR and Malaria Severity: The Center of a Perfect Storm.A method for positive and negative selection of Plasmodium falciparum platelet-mediated clumping parasites and investigation of the role of CD36.Differential PfEMP1 expression is associated with cerebral malaria pathology.Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.Correlation of hemorrhage, axonal damage, and blood-tissue barrier disruption in brain and retina of Malawian children with fatal cerebral malaria.Severity of retinopathy parallels the degree of parasite sequestration in the eyes and brains of malawian children with fatal cerebral malaria Brain swelling and death in children with cerebral malaria Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria.Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria: a retrospective case-control study*Developmental allometry and paediatric malaria.The Impact of HIV Coinfection on Cerebral Malaria Pathogenesis.Effect of mushroom Agaricus blazei on immune response and development of experimental cerebral malaria.The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice.Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding.Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection Targeting glutamine metabolism rescues mice from late-stage cerebral malaria.Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches.CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature.Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.A quantitative brain map of experimental cerebral malaria pathology.

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The neuropathology of fatal cerebral malaria in malawian children

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The neuropathology of fatal cerebral malaria in malawian children

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The neuropathology of fatal cerebral malaria in malawian children

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The neuropathology of fatal cerebral malaria in malawian children

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J.AJPATH.2011.01.016

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The American Journal of Pathology

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The neuropathology of fatal cerebral malaria in malawian children

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Hanh Huynh

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Katerina Dorovini-Zis

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Kristopher Schmidt

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Richard O Whitten

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Steve Kamiza

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Wenjiang Fu

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P2860

Molecules on the surface of the Plasmodium falciparum infected erythrocyte and their role in malaria pathogenesis and immune evasion

MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster

Gaps in the childhood malaria burden in Africa: cerebral malaria, neurological sequelae, anemia, respiratory distress, hypoglycemia, and complications of pregnancy.

High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria.

Macrophage migration inhibitory factor is associated with mortality in cerebral malaria patients in India.

Brain swelling and ischaemia in Kenyans with cerebral malaria

Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria.

Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium

Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology?

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10.1016/J.AJPATH.2011.01.016

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Malcolm Molyneux

Terrie E Taylor

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2011-05-01T00:00:00Z

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cerebral malaria

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3081150

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