Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice. - Wikidata - awgldk - TriplyDB

Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.

Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.

http://www.wikidata.org/entity/Q34841988

about

Pancreatic regulation of glucose homeostasis Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism Leptin and its cardiovascular effects: Focus on angiogenesis Alzheimer's disease and type 2 diabetes via chronic inflammatory mechanisms ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets Leptin induces inflammation-related genes in RINm5F insulinoma cells Disorders of glucose metabolism in sleep apnea.The brain is the conductor: diet-induced inflammation overlapping physiological control of body mass and metabolism.SLEEP DISORDERED BREATHING AND METABOLIC EFFECTS: EVIDENCE FROM ANIMAL MODELS Reporter islets in the eye reveal the plasticity of the endocrine pancreas Longitudinal evaluation of hepatic lipid deposition and composition in ob/ob and ob/+ control mice.The role of leptin in glucose homeostasis.Human IL6 enhances leptin action in mice.Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice.Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus.Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats.SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.Disruption of hepatic leptin signaling protects mice from age- and diet-related glucose intolerance.Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.Impaired Ca(2+) signaling in β-cells lacking leptin receptors by Cre-loxP recombination.Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus.Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis Leptin ameliorates ischemic necrosis of the femoral head in rats with obesity induced by a high-fat diet.Effects of different acute hypoxic regimens on tissue oxygen profiles and metabolic outcomes Leptin in human physiology and pathophysiology.Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.Metabolic effects of intermittent hypoxia in mice: steady versus high-frequency applied hypoxia daily during the rest period.Newer therapeutic options for children with diabetes mellitus: theoretical and practical considerations.Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats Quercetin Preserves β -Cell Mass and Function in Fructose-Induced Hyperinsulinemia through Modulating Pancreatic Akt/FoxO1 Activation Inter-organ communication and regulation of beta cell function The role of leptin in the control of insulin-glucose axis.Nutrigenomics, beta-cell function and type 2 diabetes Antenatal glucocorticoid exposure enhances the inhibition of adrenal steroidogenesis by leptin in a sex-specific fashion.Leptin administration enhances islet transplant performance in diabetic mice.Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients.Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat

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P2860

Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.

http://www.wikidata.org/entity/Q34841988

description

1999 nî lūn-bûn

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1999 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1999 թվականի հունվարին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Leptin inhibits insulin gene t ...... n leptin-deficient ob/ob mice.

@en

P2093

J F Habener

http://www.w3.org/2001/XMLSchema#string

J Seufert

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T J Kieffer

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P2860

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

Effects of the obese gene product on body weight regulation in ob/ob mice

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

Identification and expression cloning of a leptin receptor, OB-R

Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells

Metabolic control of insulin gene expression and biosynthesis.

Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR).

Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice.

Leptin inhibits insulin secretion by activation of phosphodiesterase 3B.

Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans.

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2

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96

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9892692

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