about
The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathwayAmyloid beta-protein monomer folding: free-energy surfaces reveal alloform-specific differencesEffects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicityUnified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapyTargeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeuticsDye-binding assays for evaluation of the effects of small molecule inhibitors on amyloid (aβ) self-assemblyPathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseDimer formation enhances structural differences between amyloid β-protein (1-40) and (1-42): an explicit-solvent molecular dynamics studyComplete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitorSmall-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screeningAmyloid-β protofibrils: size, morphology and synaptotoxicity of an engineered mimicNa, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly.Design and Characterization of Chemically Stabilized Aβ42 OligomersInhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption.Preparation of pure populations of covalently stabilized amyloid β-protein oligomers of specific sizes.Site-specific inhibitory mechanism for amyloid β42 aggregation by catechol-type flavonoids targeting the Lys residues.Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's diseaseAlzheimer's disease: pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents.High-speed atomic force microscopy reveals structural dynamics of amyloid β1-42 aggregates.Effects of membrane interaction and aggregation of amyloid β-peptide on lipid mobility and membrane domain structure.Amyloid beta-protein assembly as a therapeutic target of Alzheimer's disease.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patientsNicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Beta-amyloid oligomers and cellular prion protein in Alzheimer's disease.Biomarkers in Alzheimer's disease: past, present and future.Calcium signaling and amyloid toxicity in Alzheimer disease.High-resolution conformation and backbone dynamics of a soluble aggregate of apomyoglobin119.Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease.A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation.Transient formation of intermediate conformational states of amyloid-β peptide revealed by heteronuclear magnetic resonance spectroscopy.Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.Rationally designed peptoids modulate aggregation of amyloid-beta 40.Transthyretin-derived peptides as β-amyloid inhibitors.Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid beta-protein assembly and toxicity.Despite its role in assembly, methionine 35 is not necessary for amyloid beta-protein toxicityMysterious oligomerization of the amyloidogenic proteinsPolymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues.
P2860
Q24294387-6CD0A393-7711-45E0-9D53-E63C1BB1C17AQ24653927-E2670568-5AAA-44B2-84E1-268B38A74601Q24657235-2B4395F6-1DEF-44E8-974E-66A0565CCBC4Q26382049-9FB4016C-8DA9-430D-9EB0-50EB1763D8FEQ26822002-2CC03331-E8E6-4A2A-9522-D48FFC7270CAQ26852205-F095A4BC-8DA1-4E58-9E6C-348BA969B092Q26853610-4581225F-5E05-4F74-9601-2E13816DF9DCQ27012950-4D00DAFB-5605-43E6-A633-98CAB6BF187AQ27305237-C7C8124A-3887-4453-9092-369D9C31320EQ28474363-B8D4AFDA-A3CC-40A4-8C20-3666F17A2E16Q28475342-DACEEE8D-2910-42DE-B822-9F863375FFA9Q28534463-2DA893C4-BF8D-46F4-89FC-3C59A9D19FE2Q28572007-DDA610F9-F7FC-422D-88BB-0D4C25DF3937Q28821642-EA56CEC0-AC3E-4B5C-83F4-2264127BFED8Q30175697-1B5094E9-7321-45DA-87E0-BFDA921E519AQ30394852-BD5EF9D3-0008-4C6D-A33C-AF069FAB0858Q30432271-0241D80F-F414-4D5E-851D-DA51DAAA0875Q30483386-C252537E-74E7-44A4-A1B6-829331660E15Q30666219-B5D24059-F41D-4C8E-B23F-4F41BBDC57D8Q30764286-D1307900-40BE-4646-AC2E-09C7DAD164EBQ31113633-10F3E034-8A81-4A97-A2C5-C068990169E1Q33392254-745413CA-AAA0-4AF2-A3EE-9C11379050F0Q33646882-C194691D-8BDA-4665-8C28-65DF8DD399BFQ33691958-59707A8C-1842-4BAF-BB3D-3664909680D9Q33694502-9710DD27-3DC8-4CAA-9B6B-61DADC2CB69EQ33757721-AE542337-7EFB-43C0-9920-9A12A10ADD3BQ33791646-C0CF40E8-D73A-4D18-8DF7-BC7A3F9C7B92Q33799937-BCDCEC9A-C780-41CC-A304-5CFCC9545350Q33808009-CC8B9941-6559-4D8D-9C0D-83FEB851DEEEQ33813567-1CB8DB27-EECE-4A60-839F-5929FDF214B4Q33824308-707C2A41-655E-423D-AAE7-711DF376D701Q33845519-6B497CB5-067E-4441-AA49-FE14D2F1D4BCQ33893017-9EC80855-07A8-4EFA-9095-306126E41888Q33918190-AEEDD2C5-D0A9-4952-B8CF-BD586516CFF9Q33918213-E4101069-FEAB-4CB0-83C7-AA6818A296A3Q34003950-EFB9A940-D46B-477D-BFB9-686CAD5EFE8FQ34012473-738C0C85-5AC6-4416-BEEB-3C89913F00CFQ34046583-84B21B7F-F60B-426B-A006-4FE8903D77E4Q34059772-6693D022-0C55-4A1D-AB62-2DAC7B8028EBQ34074414-84E4F958-63CB-4069-8EB0-F24F6407834C
P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Amyloid beta-protein assembly and Alzheimer disease.
@ast
Amyloid beta-protein assembly and Alzheimer disease.
@en
Amyloid beta-protein assembly and Alzheimer disease.
@nl
type
label
Amyloid beta-protein assembly and Alzheimer disease.
@ast
Amyloid beta-protein assembly and Alzheimer disease.
@en
Amyloid beta-protein assembly and Alzheimer disease.
@nl
prefLabel
Amyloid beta-protein assembly and Alzheimer disease.
@ast
Amyloid beta-protein assembly and Alzheimer disease.
@en
Amyloid beta-protein assembly and Alzheimer disease.
@nl
P2093
P2860
P356
P1476
Amyloid beta-protein assembly and Alzheimer disease.
@en
P2093
David B Teplow
Minako M Hoshi
Mingfeng Yang
Robin Roychaudhuri
P2860
P304
P356
10.1074/JBC.R800036200
P407
P577
2008-10-09T00:00:00Z