Strain variations in single amino acids of the 86-kilodalton human cytomegalovirus major immediate-early protein (IE2) affect its functional and biochemical properties: implications of dynamic protein conformation.
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Analysis of human cytomegalovirus-encoded SUMO targets and temporal regulation of SUMOylation of the immediate-early proteins IE1 and IE2 during infectionThe phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression.Role of noncovalent SUMO binding by the human cytomegalovirus IE2 transactivator in lytic growth.Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replicationSUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replicationOncomodulatory signals by regulatory proteins encoded by human cytomegalovirus: a novel role for viral infection in tumor progression.Cell cycle-independent expression of immediate-early gene 3 results in G1 and G2 arrest in murine cytomegalovirus-infected cells.Human pathogens and the host cell SUMOylation system.Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomesThe putative zinc finger of the human cytomegalovirus IE2 86-kilodalton protein is dispensable for DNA binding and autorepression, thereby demarcating a concise core domain in the C terminus of the protein.PIAS1 enhances SUMO-1 modification and the transactivation activity of the major immediate-early IE2 protein of human cytomegalovirus.Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression.Importance of covalent and noncovalent SUMO interactions with the major human cytomegalovirus transactivator IE2p86 for viral infection.
P2860
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P2860
Strain variations in single amino acids of the 86-kilodalton human cytomegalovirus major immediate-early protein (IE2) affect its functional and biochemical properties: implications of dynamic protein conformation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Strain variations in single am ...... dynamic protein conformation.
@ast
Strain variations in single am ...... dynamic protein conformation.
@en
Strain variations in single am ...... major immediate-early protein
@nl
type
label
Strain variations in single am ...... dynamic protein conformation.
@ast
Strain variations in single am ...... dynamic protein conformation.
@en
Strain variations in single am ...... major immediate-early protein
@nl
prefLabel
Strain variations in single am ...... dynamic protein conformation.
@ast
Strain variations in single am ...... dynamic protein conformation.
@en
Strain variations in single am ...... major immediate-early protein
@nl
P2093
P2860
P1433
P1476
Strain variations in single am ...... dynamic protein conformation.
@en
P2093
James C Alwine
M Inmaculada Barrasa
Noam Harel
Yongjun Yu
P2860
P304
P356
10.1128/JVI.77.8.4760-4772.2003
P407
P577
2003-04-01T00:00:00Z