Human cytomegalovirus major immediate-early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3'-OH kinase pathway and the cellular kinase Akt.
about
Consensus on the role of human cytomegalovirus in glioblastomaHuman cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexesAdapting the Stress Response: Viral Subversion of the mTOR Signaling PathwayMouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesisAn invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathwayChronic viral infection and primary central nervous system malignancy.Murine cytomegalovirus m41 open reading frame encodes a Golgi-localized antiapoptotic protein.Childhood cancers: what is a possible role of infectious agents?Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensingThe phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression.Effects of simian virus 40 large and small tumor antigens on mammalian target of rapamycin signaling: small tumor antigen mediates hypophosphorylation of eIF4E-binding protein 1 late in infection.The oncogenic potential of human cytomegalovirus and breast cancer.Human cytomegalovirus activates glucose transporter 4 expression to increase glucose uptake during infectionProtein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradationNew cell-signaling pathways for controlling cytomegalovirus replication.Strain variations in single amino acids of the 86-kilodalton human cytomegalovirus major immediate-early protein (IE2) affect its functional and biochemical properties: implications of dynamic protein conformation.Frontier of epilepsy research - mTOR signaling pathway.Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection.SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replicationDetection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic targetThe role of PI3K/Akt in human herpesvirus infection: From the bench to the bedsideHCMV infection: modulating the cell cycle and cell death.Oncomodulatory signals by regulatory proteins encoded by human cytomegalovirus: a novel role for viral infection in tumor progression.Analysis of splice variants of the immediate-early 1 region of human cytomegalovirus.Transformation with oncogenic Ras and the simian virus 40 T antigens induces caspase-dependent sensitivity to fatty acid biosynthetic inhibitionHuman cytomegalovirus UL38 protein blocks apoptosis.Sirolimus for GVHD prophylaxis in allogeneic stem cell transplantation.Tuberous Sclerosis Complex Protein 2-Independent Activation of mTORC1 by Human Cytomegalovirus pUL38.Poly(A) binding protein abundance regulates eukaryotic translation initiation factor 4F assembly in human cytomegalovirus-infected cells.Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways.Roles of host and viral microRNAs in human cytomegalovirus biologyDynein mediates the localization and activation of mTOR in normal and human cytomegalovirus-infected cells.Viruses - seeking and destroying the tumor program.Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry.Interaction between simian virus 40 large T antigen and insulin receptor substrate 1 is disrupted by the K1 mutation, resulting in the loss of large T antigen-mediated phosphorylation of Akt.Interplay between Hepatitis C Virus and Redox Cell Signaling.Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway.Human cytomegalovirus protein pUL38 induces ATF4 expression, inhibits persistent JNK phosphorylation, and suppresses endoplasmic reticulum stress-induced cell death.
P2860
Q24632103-986F643B-A3B1-4200-982B-F29313BC88E8Q24676817-C8D156B5-B7F9-4B7D-8BEE-46FFAFB16BBEQ26700049-9F16B2A7-F066-4175-8EED-52D1C5472819Q28504478-164B884D-F75B-4425-9F7A-9DD74879459AQ28539677-FE7E0716-8316-41DE-9D76-D5E7F28B204CQ30480064-42FE1ED6-6B1B-430E-A2F3-392672CAFF99Q31011536-E8410E51-9F3D-450D-8213-8A89BED4BADDQ33643064-06E3488D-25C5-491D-A90F-D975A0380A3DQ33652089-C1641FCA-8F0A-4A26-B055-F7B5A9563A27Q33716504-B0EF131E-F727-4613-ACC2-9E38238377A0Q33788939-9265E689-94A1-4AC0-AE69-2D175D0F99E3Q34081724-5DA50C73-D1F2-4920-A212-7F845EF71ABEQ34529843-43882867-99FC-4C82-8442-5FBB416649FDQ34545781-9ABE3EDC-2EBE-48AC-B33B-9B640E4FFE4EQ34545941-9F9E5580-B833-49A3-915D-7FC0D6C40B87Q34793671-FA9ECC68-8CAE-4071-B56E-25A9B645F684Q34856545-CE31043E-F457-454C-8452-EE96B5E42C0BQ35014198-D5ED8291-7284-43C4-844E-19158C045D27Q35087457-5DCFD0F1-E4B7-4896-8B3B-4FB9868D8205Q35123249-2851B9EC-A570-4F50-8D26-944B639E7BF8Q35370135-F422C45A-22F3-438D-9329-2EAF752360B0Q35582498-38FDB359-3ABA-4488-BDF3-5C8092F79CBEQ35613805-E1921C49-B25E-4AEF-9D9A-AA06115FB3B4Q35671858-0C928454-157D-43B1-B368-2D37CB5D5EA2Q35703488-C12BA2DE-BCD0-4F3B-97CE-0E6CD38AE798Q35760413-4F3FCE5E-DE08-4F62-827B-1E212E7EFEBBQ35785145-FC6F1A99-F9F4-4771-BA9F-86EC6F16AD2CQ35845541-46FA6A46-9E78-40C5-8C80-F4C53C24CCD4Q35861166-93696C10-FBEC-47D1-9B84-4EE286CB8765Q35889417-14847A59-A5FD-4319-8059-EA3227E0C3B8Q35921644-A88C43D9-5DA7-418C-B754-15E1DB8B1471Q36060243-05EB8F8A-EC70-44A7-B9CC-3BAD1DDEB2BAQ36240899-D250A6AF-1028-4AF3-9F4B-7F617FCAF5A0Q36318145-418D8888-7F51-46B7-A1DE-C41FD02E0241Q36451941-45EB0DE1-0431-4210-9DF0-D8A3C065C071Q36540107-58E26474-FD95-49EC-99B9-6511489A3347Q36790471-18C64605-EBE6-4B58-90F6-A5ED71A387ECQ36890676-2500B3C6-AD06-4B81-8191-F0C33E887925Q37003173-18F83232-0367-4CE9-ABFA-9A459BD188B5Q37145200-90734202-00E3-4BCF-ABC7-157DF341BB6E
P2860
Human cytomegalovirus major immediate-early proteins and simian virus 40 large T antigen can inhibit apoptosis through activation of the phosphatidylinositide 3'-OH kinase pathway and the cellular kinase Akt.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@ast
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@en
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@nl
type
label
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@ast
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@en
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@nl
prefLabel
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@ast
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@en
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@nl
P2860
P1433
P1476
Human cytomegalovirus major im ...... y and the cellular kinase Akt.
@en
P2093
James C Alwine
Yongjun Yu
P2860
P304
P356
10.1128/JVI.76.8.3731-3738.2002
P407
P577
2002-04-01T00:00:00Z