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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseImpaired T-Cell Function in B-Cell Lymphoma: A Direct Consequence of Events at the Immunological Synapse?VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responsesRegulation of cytokine production by virus-specific CD8 T cells in the lungs.Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.Leukocyte migration and graft-versus-host disease.Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibitionAdhesion shapes T cells for prompt and sustained T-cell receptor signalling.Formation of a mast cell synapse: Fc epsilon RI membrane dynamics upon binding mobile or immobilized ligands on surfaces.Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide.WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts.Ultrastructural localization of extracellular matrix proteins of the lymph node cortex: evidence supporting the reticular network as a pathway for lymphocyte migration.Maturation-dependent licensing of naive T cells for rapid TNF production.Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1.Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of LckThe endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreadingAntigen-specific blocking of CD4-specific immunological synapse formation using BPI and current therapies for autoimmune diseases.Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP.Disintegrins: integrin selective ligands which activate integrin-coupled signaling and modulate leukocyte functions.Therapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: two-edged swords?Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells.Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effectsThe emerging role of protein kinase Cθ in cytoskeletal signaling.Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug.CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes.Leukocyte integrin Mac-1 promotes acute cardiac allograft rejection.Targeting costimulatory pathways for tumor immunotherapy.Compartmentalization of ITAM and integrin signaling by adapter molecules.Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponsesTranscriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype.CD98hc facilitates B cell proliferation and adaptive humoral immunity.Genetic deficiency of Itgb2 or ItgaL prevents autoimmune diabetes through distinctly different mechanisms in NOD/LtJ mice.Prolonged contact with dendritic cells turns lymph node-resident NK cells into anti-tumor effectors.Leukocyte integrins and their ligand interactions.Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.Intercellular exchange of proteins: the immune cell habit of sharing.Interplay of polarity proteins and GTPases in T-lymphocyte function.Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.Viral oncomiR spreading between B and T cells is employed by Kaposi's sarcoma herpesvirus to induce non-cell-autonomous target gene regulation.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The immunological synapse: integrins take the stage.
@ast
The immunological synapse: integrins take the stage.
@en
The immunological synapse: integrins take the stage.
@nl
type
label
The immunological synapse: integrins take the stage.
@ast
The immunological synapse: integrins take the stage.
@en
The immunological synapse: integrins take the stage.
@nl
prefLabel
The immunological synapse: integrins take the stage.
@ast
The immunological synapse: integrins take the stage.
@en
The immunological synapse: integrins take the stage.
@nl
P1476
The immunological synapse: integrins take the stage
@en
P2093
Tasha N Sims
P304
P356
10.1034/J.1600-065X.2002.18610.X
P577
2002-08-01T00:00:00Z