Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis
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A computational screen for type I polyketide synthases in metagenomics shotgun dataStructure and Mechanism of the trans -Acting Acyltransferase from the Disorazole SynthaseStructure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog FoldA Close Look at a Ketosynthase from a Trans-Acyltransferase Modular Polyketide SynthaseEvolution of polyketide synthases in bacteriaNovel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.Identification of the missing trans-acting enoyl reductase required for phthiocerol dimycocerosate and phenolglycolipid biosynthesis in Mycobacterium tuberculosisPolyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae).C-S bond cleavage by a polyketide synthase domain.Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase.Cloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in "Streptomyces carzinostaticus"Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations.Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes.Metagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissoluta.Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42.ASMPKS: an analysis system for modular polyketide synthasesRecognition of (2S)-aminomalonyl-acyl carrier protein (ACP) and (2R)-hydroxymalonyl-ACP by acyltransferases in zwittermicin A biosynthesisProtein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes.Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender unitsLeinamycin E1 acting as an anticancer prodrug activated by reactive oxygen speciesBiosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.Characterization of the lnmKLM genes unveiling key intermediates for β-alkylation in leinamycin biosynthesis.Polyketide and non-ribosomal peptide synthases: falling together by coming apart.Type I pyridoxal 5'-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly linesDraft Genome Sequence of Marine-Derived Streptomyces sp. TP-A0873, a Producer of a Pyrrolizidine Alkaloid Bohemamine.Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.The enzymology of combinatorial biosynthesis.Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.A singular enzymatic megacomplex from Bacillus subtilisSynthesis and evaluation of 8,4'-dideshydroxy-leinamycin revealing new insights into the structure-activity relationship of the anticancer natural product leinamycin.Type I polyketide synthases that require discrete acyltransferases.Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthasesCharacterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968Polyketide proofreading by an acyltransferase-like enzyme.In Vitro Investigation of Crosstalk between Fatty Acid and Polyketide Synthases in the Andrimid Biosynthetic Assembly Line.Characterization of LnmO as a pathway-specific Crp/Fnr-type positive regulator for leinamycin biosynthesis in Streptomyces atroolivaceus and its application for titer improvement.
P2860
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P2860
Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Type I polyketide synthase req ...... se for polyketide biosynthesis
@ast
Type I polyketide synthase req ...... se for polyketide biosynthesis
@en
Type I polyketide synthase req ...... se for polyketide biosynthesis
@nl
type
label
Type I polyketide synthase req ...... se for polyketide biosynthesis
@ast
Type I polyketide synthase req ...... se for polyketide biosynthesis
@en
Type I polyketide synthase req ...... se for polyketide biosynthesis
@nl
prefLabel
Type I polyketide synthase req ...... se for polyketide biosynthesis
@ast
Type I polyketide synthase req ...... se for polyketide biosynthesis
@en
Type I polyketide synthase req ...... se for polyketide biosynthesis
@nl
P2093
P2860
P356
P1476
Type I polyketide synthase req ...... se for polyketide biosynthesis
@en
P2093
Gong-Li Tang
Yi-Qiang Cheng
P2860
P304
P356
10.1073/PNAS.0537286100
P407
P577
2003-02-21T00:00:00Z