In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.
about
Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743Predominately Uncultured Microbes as Sources of Bioactive AgentsMicrobial communities and bioactive compounds in marine sponges of the family irciniidae-a reviewRecognition of (2S)-aminomalonyl-acyl carrier protein (ACP) and (2R)-hydroxymalonyl-ACP by acyltransferases in zwittermicin A biosynthesisComparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.Bryostatins: biological context and biotechnological prospects.Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthaseGenetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering.Polyketide proofreading by an acyltransferase-like enzyme.The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.Boronated tartrolon antibiotic produced by symbiotic cellulose-degrading bacteria in shipworm gills.Assembly of long error-prone reads using de Bruijn graphs.Metagenomic approaches to natural products from free-living and symbiotic organisms.Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.Microbial natural products: molecular blueprints for antitumor drugs.Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases.Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.Recent advances in the biosynthesis of unusual polyketide synthase substrates.Considerations of the chemical biology of microbial natural products provide an effective drug discovery strategy.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Twofold polyketide branching by a stereoselective enzymatic Michael addition.Bacterial biosynthetic gene clusters encoding the anti-cancer haterumalide class of molecules: biogenesis of the broad spectrum antifungal and anti-oomycete compound, oocydin A.Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq.The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide.Exploring chemical diversity of α-pyrone antibiotics: molecular basis of myxopyronin biosynthesis.The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS.Parallel lives of symbionts and hosts: chemical mutualism in marine animals.PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.
P2860
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P2860
In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
In vivo and in vitro trans-acy ...... an uncultured marine symbiont.
@ast
In vivo and in vitro trans-acy ...... an uncultured marine symbiont.
@en
type
label
In vivo and in vitro trans-acy ...... an uncultured marine symbiont.
@ast
In vivo and in vitro trans-acy ...... an uncultured marine symbiont.
@en
prefLabel
In vivo and in vitro trans-acy ...... an uncultured marine symbiont.
@ast
In vivo and in vitro trans-acy ...... an uncultured marine symbiont.
@en
P2093
P2860
P1476
In vivo and in vitro trans-acy ...... an uncultured marine symbiont
@en
P2093
Christopher M Rath
Christopher M Thomas
David H Sherman
Jennifer A Shields
Joanne Hothersall
Margo G Haygood
Nicole B Lopanik
Tonia J Buchholz
P2860
P304
P356
10.1016/J.CHEMBIOL.2008.09.013
P577
2008-11-01T00:00:00Z