Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin - Wikidata - awgldk - TriplyDB

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

http://www.wikidata.org/entity/Q34871780

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CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.Survivin: a unique target for tumor therapy Localization and upregulation of survivin in cancer health disparities: a clinical perspective Targeting of erbB3 receptor to overcome resistance in cancer treatment Nuclear survivin expression: a prognostic factor for the response to taxane-platinum chemotherapy in patients with advanced non-small cell lung cancer.Prognostic value and targeted inhibition of survivin expression in esophageal adenocarcinoma and cancer-adjacent squamous epithelium Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML)Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childho The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer Targeting survivin in cancer: novel drug development approaches.MicroRNA regulation and therapeutic targeting of survivin in cancer.Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST).A novel antagonist to the inhibitors of apoptosis (IAPs) potentiates cell death in EGFR-overexpressing non-small-cell lung cancer cells Influence of survivin-targeted therapy on chemosensitivity in the treatment of acute myeloid leukemia.Prognostic relevance of survivin in pancreatic endocrine tumors Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines Pro-apoptotic effects of rHSG on C6 glioma cells.Prognostic significance of survivin, β-catenin and p53 expression in urothelial carcinoma.IWR-1 inhibits epithelial-mesenchymal transition of colorectal cancer cells through suppressing Wnt/β-catenin signaling as well as survivin expression Sensitization of estrogen receptor-positive breast cancer cell lines to 4-hydroxytamoxifen by isothiocyanates present in cruciferous plants.Design and characterization of the tumor vaccine MGN1601, allogeneic fourfold gene-modified vaccine cells combined with a TLR-9 agonist.Cell survival and metastasis regulation by Akt signaling in colorectal cancer Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma.miR-138-5p contributes to cell proliferation and invasion by targeting Survivin in bladder cancer cells.Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer.Targeting the Fas/FasL signaling pathway in cancer therapy.Apoptosis-modulating drugs for improved cancer therapy.Increasing the range of drug targets: interacting peptides provide leads for the development of oncoprotein inhibitors.Monitoring survivin expression in cancer: implications for prognosis and therapy.Hypoxic tumor microenvironment in advanced retinoblastoma.Nuclear, but not cytoplasmic, localization of survivin as a negative prognostic factor for survival in upper urinary tract urothelial carcinoma.YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy.Guadecitabine (SGI-110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin.Dual silencing of Bcl-2 and Survivin by HSV-1 vector shows better antitumor efficacy in higher PKR phosphorylation tumor cells in vitro and in vivo.Transcriptional upregulation of HNF-1β by NF-κB in ovarian clear cell carcinoma modulates susceptibility to apoptosis through alteration in bcl-2 expression.Downregulation of Survivin by shRNA Inhibits Invasion and Enhances the Radiosensitivity of Laryngeal Squamous Cell Carcinoma.Prevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics.Small interfering RNA-mediated suppression of serum response factor, E2-promotor binding factor and survivin in non-small cell lung cancer cell lines by non-viral transfection.Survivin small interfering RNA suppresses glioblastoma growth by inducing cellular apoptosis.

P2860

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P2860

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

http://www.wikidata.org/entity/Q34871780

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@ast

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@en

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@nl

type

label

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@ast

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@en

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@nl

prefLabel

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@ast

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

@en

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

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Molecular Cancer

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Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

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Ariel Lopez-Chavez

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Deborah Citrin

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John C Morris

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John E Janik

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Ronan J Kelly

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P2860

Control of apoptosis and mitotic spindle checkpoint by survivin

Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties

Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement

Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

HBXIP functions as a cofactor of survivin in apoptosis suppression

Hsp60 regulation of tumor cell apoptosis

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

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