Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions
about
Analysis of mitotic phosphorylation of borealinMolecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosisSurvivin monomer plays an essential role in apoptosis regulationImpairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complexThreonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitroThe Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeresCentromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENPErbB receptors: from oncogenes to targeted cancer therapiesSurvivin - biology and potential as a therapeutic target in oncologyThe mitotic regulator Survivin binds as a monomer to its functional interactor BorealinStructural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human SurvivinSurvivin enhances Aurora-B kinase activity and localizes Aurora-B in human cellsInterleukin enhancer-binding factor 3/NF110 is a target of YM155, a suppressant of survivinPerformance of survivin mRNA as a biomarker for bladder cancer in the prospective study UroScreenAurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line.Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma.Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublinesCharacterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin.Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.Understanding IAP function and regulation: a view from Drosophila.A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy.Change in Expression of Survivin Caused by Using Oxaliplatin in HCT116 Colon Cancer CellsImpacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivinSurvivin, versatile modulation of cell division and apoptosis in cancer.Detection of femtomolar level osteosarcoma-related gene via a chronocoulometric DNA biosensor based on nanostructure gold electrode.Transarterial chemoembolization of hepatocellular carcinoma in a rat model: the effect of additional injection of survivin siRNA to the treatment protocolExpression of survivin in human gastric carcinoma and gastric carcinoma model of rats.Human survivin is a kinetochore-associated passenger protein.Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins.The chromosomal passenger complex: guiding Aurora-B through mitosis.Disabling the mitotic spindle and tumor growth by targeting a cavity-induced allosteric site of survivinFocused grid-based resampling for protein docking and mapping.A single amino acid change (Asp 53 --> Ala53) converts Survivin from anti-apoptotic to pro-apoptoticThe chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.IAP-targeted therapies for cancer.Effects of full-length borealin on the composition and protein-protein interaction activity of a binary chromosomal passenger complex.Immunohistochemical expression and serum level of survivin protein in colorectal cancer patients.Survivin in solid tumors: rationale for development of inhibitors.
P2860
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P2860
Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
Crystal structure of human sur ...... usual alpha-helical extensions
@ast
Crystal structure of human sur ...... usual alpha-helical extensions
@en
Crystal structure of human sur ...... usual alpha-helical extensions
@en-gb
Crystal structure of human sur ...... usual alpha-helical extensions
@nl
type
label
Crystal structure of human sur ...... usual alpha-helical extensions
@ast
Crystal structure of human sur ...... usual alpha-helical extensions
@en
Crystal structure of human sur ...... usual alpha-helical extensions
@en-gb
Crystal structure of human sur ...... usual alpha-helical extensions
@nl
prefLabel
Crystal structure of human sur ...... usual alpha-helical extensions
@ast
Crystal structure of human sur ...... usual alpha-helical extensions
@en
Crystal structure of human sur ...... usual alpha-helical extensions
@en-gb
Crystal structure of human sur ...... usual alpha-helical extensions
@nl
P2093
P3181
P1433
P1476
Crystal structure of human sur ...... usual alpha-helical extensions
@en
P2093
D A Skoufias
L Chantalat
O Dideberg
R L Margolis
P3181
P356
10.1016/S1097-2765(00)00019-8
10.1016/S1097-2765(05)00020-1
P407
P577
2000-07-01T00:00:00Z