Geminal dialkyl derivatives of N-substituted pantothenamides: synthesis and antibacterial activity.
about
Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activityPantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivatedExploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase.A cross-metathesis approach to novel pantothenamide derivatives.Triazole Substitution of a Labile Amide Bond Stabilizes Pantothenamides and Improves Their Antiplasmodial Potency.Stereochemical modification of geminal dialkyl substituents on pantothenamides alters antimicrobial activityRecent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development.Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides.Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis.
P2860
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P2860
Geminal dialkyl derivatives of N-substituted pantothenamides: synthesis and antibacterial activity.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@ast
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@en
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@nl
type
label
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@ast
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@en
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@nl
prefLabel
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@ast
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@en
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@nl
P2093
P2860
P1476
Geminal dialkyl derivatives of ...... is and antibacterial activity.
@en
P2093
Karine Auclair
Kenward Vong
T Olukayode Akinnusi
P2860
P304
P356
10.1016/J.BMC.2011.02.053
P407
P577
2011-03-04T00:00:00Z