Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections - Wikidata - awgldk - TriplyDB

Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

http://www.wikidata.org/entity/Q28205718

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The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes Structure of the Type III Pantothenate Kinase from Bacillus anthracis at 2.0 Å Resolution: Implications for Coenzyme A-Dependent Redox Biology † , ‡Structural and Functional Studies of Aspergillus clavatus N 5 -Carboxyaminoimidazole Ribonucleotide Synthetase,Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumoniae and Staphylococcus aureus Characterization of a new pantothenate kinase isoform from Helicobacter pylori Crystal structure of a type III pantothenate kinase: insight into the mechanism of an essential coenzyme A biosynthetic enzyme universally distributed in bacteria Identification of gene targets against dormant phase Mycobacterium tuberculosis infections Pantothenate kinase from the thermoacidophilic archaeon Picrophilus torridus.Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity Challenges of antibacterial discovery Identification of group A Streptococcus antigenic determinants upregulated in vivo.Changes in the Staphylococcus aureus transcriptome during early adaptation to the lung.Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated Geminal dialkyl derivatives of N-substituted pantothenamides: synthesis and antibacterial activity.Synthesis of 4'-aminopantetheine and derivatives to probe aminoglycoside N-6'-acetyltransferase The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.New advances in antibiotic development and discovery.A cross-metathesis approach to novel pantothenamide derivatives.Biosynthesis of Pantothenic Acid and Coenzyme A.Stereochemical modification of geminal dialkyl substituents on pantothenamides alters antimicrobial activity Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides.Intrahost Evolution of Methicillin-Resistant Staphylococcus aureus USA300 Among Individuals With Reoccurring Skin and Soft-Tissue Infections.Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.Antimicrobial activity of pantothenol against staphylococci possessing a prokaryotic type II pantothenate kinase.Pantethine rescues phosphopantothenoylcysteine synthetase and phosphopantothenoylcysteine decarboxylase deficiency in Escherichia coli but not in Pseudomonas aeruginosa.Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.4'-phosphopantetheine and coenzyme A biosynthesis in plants.Active-site residues and amino acid specificity of the bacterial 4'-phosphopantothenoylcysteine synthetase CoaB.A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A.Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite.Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis.Role of prokaryotic type I and III pantothenate kinases in the coenzyme A biosynthetic pathway of Bacillus subtilis.

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

http://www.wikidata.org/entity/Q28205718

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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type

label

Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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AAC.47.6.2051-2055.2003

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Antimicrobial Agents and Chemotherapy

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

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P2093

Anthony E Choudhry

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Cynthia Kinsland

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James R Brown

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John P Broskey

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Kapila Ratnam

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Magdalena Zalacain

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Mark A Seefeld

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Richard W Egolf

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Tadhg P Begley

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Thomas W Ku

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P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics

Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Purification and characterization of phosphopantetheine adenylyltransferase from Escherichia coli

Whole genome sequencing of meticillin-resistant Staphylococcus aureus

Cloning, sequencing, and expression of the pantothenate kinase (coaA) gene of Escherichia coli

Comparative genome sequencing for discovery of novel polymorphisms in Bacillus anthracis

Kinetics and regulation of pantothenate kinase from Escherichia coli

Separate enzymes catalyze the final two steps of coenzyme A biosynthesis in Brevibacterium ammoniagenes: purification of pantetheine phosphate adenylyltransferase

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2051-5

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10.1128/AAC.47.6.2051-2055.2003

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6

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47

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2003-06-01T00:00:00Z

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10748334

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12760898

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infectious disease

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155856

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