Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

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http://www.wikidata.org/entity/Q34882994
New insights into decapping enzymes and selective mRNA decayCytoplasmic mRNA turnover and ageingLoss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defectsApplications of Phosphate Modification and Labeling to Study (m)RNA Caps.DcpS is a transcript-specific modulator of RNA in mammalian cells.Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.Adenylylsulfate-ammonia adenylyltransferase activity is another inherent property of Fhit proteins.Identification of Fhit as a post-transcriptional effector of Thymidine Kinase 1 expression.An excess of catalytically required motions inhibits the scavenger decapping enzyme.mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translationImpact of FHIT loss on the translation of cancer-associated mRNAs.New interactions between tumor suppressor Fhit protein and a nonhydrolyzable analog of its AP4 A substrate.Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.Loss of fragile histidine triad (Fhit) protein expression alters the translation of cancer-associated mRNAs.
P2860

Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.

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http://www.wikidata.org/entity/Q34882994
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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2014年論文
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Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@ast
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@en
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
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label
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@ast
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@en
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@nl
prefLabel
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@ast
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@en
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Elimination of cap structures ...... Aph1/FHIT together with DcpS.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932