Discovery of new GPCR biology: one receptor structure at a time.
about
Crystal structure of a lipid G protein-coupled receptorThe impact of GPCR structures on pharmacology and structure-based drug designTools for GPCR drug discovery.Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environmentsBiophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug DesignGα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years laterChemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signallingModeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugsStructure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional ImplicationsTopography prediction of helical transmembrane proteins by a new modification of the sliding window method.The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins.Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkShowcasing modern molecular dynamics simulations of membrane proteins through G protein-coupled receptors.Hydrophobicity profiles in G protein-coupled receptor transmembrane helical domains.Bihelix: Towards de novo structure prediction of an ensemble of G-protein coupled receptor conformations.Characterizing and predicting the functional and conformational diversity of seven-transmembrane proteins.GPCR 3D homology models for ligand screening: lessons learned from blind predictions of adenosine A2a receptor complex.Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.Rhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors.Emotion: The Self-regulatory Sense.Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.AT1 receptor induced alterations in histone H2A reveal novel insights into GPCR control of chromatin remodeling.Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation.Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system.Signal transduction by protease-activated receptorsStructural requirements of bitter taste receptor activation.Modern homology modeling of G-protein coupled receptors: which structural template to use?Mapping the druggable allosteric space of G-protein coupled receptors: a fragment-based molecular dynamics approach.Structural basis for μ-opioid receptor binding and activation.The year in G protein-coupled receptor research.High-throughput expression and purification of membrane proteins.VITAL NMR: using chemical shift derived secondary structure information for a limited set of amino acids to assess homology model accuracy.G-protein-coupled receptor heteromer dynamics.Adenosine A2A receptor is involved in cell surface expression of A2B receptor.Conservation of molecular interactions stabilizing bovine and mouse rhodopsin.Modeling G Protein-Coupled Receptors: a Concrete PossibilityG-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.Docking-based virtual screening for ligands of G protein-coupled receptors: not only crystal structures but also in silico models.
P2860
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P2860
Discovery of new GPCR biology: one receptor structure at a time.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Discovery of new GPCR biology: one receptor structure at a time.
@ast
Discovery of new GPCR biology: one receptor structure at a time.
@en
Discovery of new GPCR biology: one receptor structure at a time.
@nl
type
label
Discovery of new GPCR biology: one receptor structure at a time.
@ast
Discovery of new GPCR biology: one receptor structure at a time.
@en
Discovery of new GPCR biology: one receptor structure at a time.
@nl
prefLabel
Discovery of new GPCR biology: one receptor structure at a time.
@ast
Discovery of new GPCR biology: one receptor structure at a time.
@en
Discovery of new GPCR biology: one receptor structure at a time.
@nl
P2860
P1433
P1476
Discovery of new GPCR biology: one receptor structure at a time.
@en
P2093
Michael A Hanson
Raymond C Stevens
P2860
P356
10.1016/J.STR.2008.12.003
P577
2009-01-01T00:00:00Z