The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis
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Pentavalent antimonials: new perspectives for old drugsUnresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites.Therapy with sodium stibogluconate in stearylamine-bearing liposomes confers cure against SSG-resistant Leishmania donovani in BALB/c miceDrug resistance in leishmaniasisEvaluation of Leishmania donovani protein disulfide isomerase as a potential immunogenic protein/vaccine candidate against visceral LeishmaniasisLeishmania donovani isolates with antimony-resistant but not -sensitive phenotype inhibit sodium antimony gluconate-induced dendritic cell activation.Endogenous IL-13 plays a crucial role in liver granuloma maturation during Leishmania donovani infection, independent of IL-4Rα-responsive macrophages and neutrophils.Use of antimony in the treatment of leishmaniasis: current status and future directions.Antimony resistance in leishmania, focusing on experimental research.Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani.Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes.Cutaneous leishmaniasis: therapeutic strategies and future directions.The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India.Lower nitric oxide susceptibility of trivalent antimony-resistant amastigotes of Leishmania infantum.A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani.Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages.Cationic liposomal sodium stibogluconate (SSG), a potent therapeutic tool for treatment of infection by SSG-sensitive and -resistant Leishmania donovani.Erythrocyte glutathione status in human visceral leishmaniasis.Resistance of Leishmania donovani to sodium stibogluconate is related to the expression of host and parasite gamma-glutamylcysteine synthetase.Sodium stibogluconate resistance in Leishmania donovani correlates with greater tolerance to macrophage antileishmanial responses and trivalent antimony therapy.
P2860
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P2860
The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The in vivo susceptibility of ...... iting glutathione biosynthesis
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The in vivo susceptibility of ...... iting glutathione biosynthesis
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The in vivo susceptibility of ...... iting glutathione biosynthesis
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type
label
The in vivo susceptibility of ...... iting glutathione biosynthesis
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The in vivo susceptibility of ...... iting glutathione biosynthesis
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The in vivo susceptibility of ...... iting glutathione biosynthesis
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prefLabel
The in vivo susceptibility of ...... iting glutathione biosynthesis
@ast
The in vivo susceptibility of ...... iting glutathione biosynthesis
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The in vivo susceptibility of ...... iting glutathione biosynthesis
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P2093
P2860
P1476
The in vivo susceptibility of ...... iting glutathione biosynthesis
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P2093
A B Mullen
K C Carter
O C Pereira
P2860
P304
P356
10.1128/AAC.47.5.1529-1535.2003
P407
P577
2003-05-01T00:00:00Z