Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
about
A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors.Chemoenzymatic synthesis of α2-3-sialylated carbohydrate epitopes.P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironmentNovel uses for anti-platelet agents as anti-inflammatory drugs.Therapeutic targeting of molecules involved in leukocyte-endothelial cell interactions.Selectin inhibitors and their proposed role in ischemia and reperfusion.Non-carbohydrate inhibitors of the lectin DC-SIGN.Covalent immobilization of p-selectin enhances cell rolling.Inhibitors of selectin functions in the treatment of inflammatory skin disorders.New sialyl Lewis(x) mimic containing an alpha-substituted beta(3)-amino acid spacer.Chemoenzymatic synthesis of functional sialyl Lewis(x) mimetics with a heteroaromatic core.Carbohydrate-PNA and aptamer-PNA conjugates for the spatial screening of lectins and lectin assemblies.Sialyl Lewis(x): a "pre-organized water oligomer"?Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease.A new approach to explore the binding space of polysaccharide-based ligands: selectin antagonists.Chemical preparation of sialyl Lewis x using an enzymatically synthesized sialoside building block.Acyclic tethers mimicking subunits of polysaccharide ligands: selectin antagonistsHighly conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I form a network of disulfide bonds and include a thiol that affects enzyme activity.Sticky wickets in lower nephron nephrosis.Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration.Expression, purification, and refolding of active recombinant human E-selectin lectin and EGF domains in Escherichia coli.Modulating Lectin Inhibition withN-Glycosyl-1,2,3-triazole ScaffoldsBiosynthesis and Biological Activity of Carbasugars
P2860
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P2860
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Design and synthesis of sialyl Lewis
@nl
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@ast
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@en
type
label
Design and synthesis of sialyl Lewis
@nl
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@ast
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@en
prefLabel
Design and synthesis of sialyl Lewis
@nl
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@ast
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@en
P2860
P356
P1476
Design and synthesis of sialyl Lewis(x) mimics as E- and P-selectin inhibitors.
@en
P2093
Bert E Thomas
Neelu Kaila
P2860
P304
P356
10.1002/MED.10018
P577
2002-11-01T00:00:00Z