Differential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistance
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Dihydroceramides: From Bit Players to Lead ActorsAblation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitroRole of ceramide in diabetes mellitus: evidence and mechanisms.Secretory phospholipase-A2 and fatty acid composition in oral reactive lesions: a cross-sectional studySphingolipids in obesity, type 2 diabetes, and metabolic disease.Prosteatotic genes are associated with unsaturated fat suppression of saturated fat-induced hepatic steatosis in C57BL/6 mice.Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activitySphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesisSphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes.Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes.Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: Mechanisms of lipotoxicity.Increase of palmitic acid concentration impairs endothelial progenitor cell and bone marrow-derived progenitor cell bioavailability: role of the STAT5/PPARγ transcriptional complex.Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signalingMetabolomic profiling reveals a role for caspase-2 in lipoapoptosisSphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 production and signaling in diet-induced obesity.Reduced quality and accelerated follicle loss with female reproductive aging - does decline in theca dehydroepiandrosterone (DHEA) underlie the problem?Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.Mechanistic interplay between ceramide and insulin resistanceFads1 and 2 are promoted to meet instant need for long-chain polyunsaturated fatty acids in goose fatty liver.Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity.Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes.Dihydroceramide-desaturase-1-mediated caspase 9 activation through ceramide plays a pivotal role in palmitic acid-induced HepG2 cell apoptosis.Sphingolipid regulators of cellular dysfunction in Type 2 diabetes mellitus: a systems overview.
P2860
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P2860
Differential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistance
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2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Differential regulation of dih ...... cations for insulin resistance
@ast
Differential regulation of dih ...... cations for insulin resistance
@en
Differential regulation of dih ...... cations for insulin resistance
@nl
type
label
Differential regulation of dih ...... cations for insulin resistance
@ast
Differential regulation of dih ...... cations for insulin resistance
@en
Differential regulation of dih ...... cations for insulin resistance
@nl
prefLabel
Differential regulation of dih ...... cations for insulin resistance
@ast
Differential regulation of dih ...... cations for insulin resistance
@en
Differential regulation of dih ...... cations for insulin resistance
@nl
P2093
P2860
P356
P1476
Differential regulation of dih ...... cations for insulin resistance
@en
P2093
Jessica Ross
L Ashley Cowart
Sarah E Brice
Tuoyu Geng
P2860
P304
16596-16605
P356
10.1074/JBC.M110.186916
P407
P577
2011-03-15T00:00:00Z