Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2. - Wikidata - awgldk - TriplyDB

Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

http://www.wikidata.org/entity/Q34952541

about

Dysregulation and restoration of translational homeostasis in fragile X syndrome Altered Neuronal and Circuit Excitability in Fragile X Syndrome.Channelopathy pathogenesis in autism spectrum disorders Channelopathies and dendritic dysfunction in fragile X syndrome.Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes The unstable repeats--three evolving faces of neurological disease The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back mTOR and MAPK: from localized translation control to epilepsy Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.Etiology of a genetically complex seizure disorder in Celf4 mutant mice From FMRP function to potential therapies for fragile X syndrome.Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels Fragile X Mental Retardation Protein expression in the retina is regulated by light New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes.Dysregulated nitric oxide signaling as a candidate mechanism of fragile X syndrome and other neuropsychiatric disorders.Distribution and functional expression of Kv4 family α subunits and associated KChIP β subunits in the bed nucleus of the stria terminalis.Increasing our understanding of human cognition through the study of Fragile X Syndrome.FRAGILE X SYNDROME: PSYCHIATRIC MANIFESTATIONS, ASSESSMENT AND EMERGING THERAPIES Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease.Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.Impaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome.The Shaping of Two Distinct Dendritic Spikes by A-Type Voltage-Gated K(+) Channels Dynamic regulation of synaptic maturation state by voltage-gated A-type K+ channels in CA1 hippocampal pyramidal neurons.Aberrant dendritic excitability: a common pathophysiology in CNS disorders affecting memory?The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum FMRP regulates actin filament organization via the armadillo protein p0071.Loss of functional A-type potassium channels in the dendrites of CA1 pyramidal neurons from a mouse model of fragile X syndrome.Local plasticity of dendritic excitability can be autonomous of synaptic plasticity and regulated by activity-based phosphorylation of Kv4.2.Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins Epilepsy in four genetically determined syndromes of intellectual disability.Dendritic protein synthesis in the normal and diseased brain.Fragile X mental retardation protein and synaptic plasticity IA channels: diverse regulatory mechanisms.Multifarious Functions of the Fragile X Mental Retardation Protein.Genetic and Pharmacological Reversibility of Phenotypes in Mouse Models of Autism Spectrum Disorder.

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Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

http://www.wikidata.org/entity/Q34952541

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Fragile X mental retardation p ...... f the potassium channel Kv4.2.

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Fragile X mental retardation p ...... f the potassium channel Kv4.2.

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Fragile X mental retardation p ...... f the potassium channel Kv4.2.

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Fragile X mental retardation p ...... f the potassium channel Kv4.2.

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Fragile X mental retardation p ...... f the potassium channel Kv4.2.

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JNEUROSCI.6661-10.2011

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Journal of Neuroscience

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Fragile X mental retardation p ...... f the potassium channel Kv4.2.

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P2093

Andreas Jeromin

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Christina Gross

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Dan L Pong

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Gary J Bassell

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Xiaodi Yao

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P2860

Correction of fragile X syndrome in mice.

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

Advances in the treatment of fragile X syndrome

A novel function for fragile X mental retardation protein in translational activation

Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses

Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein

The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits

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10.1523/JNEUROSCI.6661-10.2011

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