Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions. - Wikidata - awgldk - TriplyDB

Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions.

Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions.

http://www.wikidata.org/entity/Q34963520

about

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway Succinate dehydrogenase 5 (SDH5) regulates glycogen synthase kinase 3β-β-catenin-mediated lung cancer metastasis Mutant p53: One, No One, and One Hundred Thousand The network of pluripotency, epithelial-mesenchymal transition, and prognosis of breast cancer DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.The rebel angel: mutant p53 as the driving oncogene in breast cancer.Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.The role of MDM2 and MDM4 in breast cancer development and prevention.PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition.The role of miR-200a in mammalian epithelial cell transformation.Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells.LAMC2 enhances the metastatic potential of lung adenocarcinoma.Serum LAMC2 enhances the prognostic value of a multi-parametric panel in non-small cell lung cancer.P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition Mammary epithelial cell polarity is regulated differentially by p73 isoforms via epithelial-to-mesenchymal transition.Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays.Involvement of p53 in insulin-like growth factor binding protein-3 regulation in the breast cancer cell response to DNA damage.Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells.P63 regulates tubular formation via epithelial-to-mesenchymal transition Epstein-Barr virus latent membrane protein 2 effects on epithelial acinus development reveal distinct requirements for the PY and YEEA motifs Effect of RhoC on the epithelial-mesenchymal transition process induced by TGF-β1 in lung adenocarcinoma cells Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion.Slug expression in mouse skin and skin tumors is not regulated by p53.Ubiquitination and the Ubiquitin-Proteasome System as regulators of transcription and transcription factors in epithelial mesenchymal transition of cancer.Epithelial to mesenchymal transition in the pathogenesis of uterine malignant mixed Müllerian tumours: the role of ubiquitin proteasome system and therapeutic opportunities.Tumour suppressor gene function in carcinoma-associated fibroblasts: from tumour cells via EMT and back again?Mutant p53 in cancer: new functions and therapeutic opportunities.Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.p53 regulates cytoskeleton remodeling to suppress tumor progression.Mutant p53 promotes epithelial-mesenchymal plasticity and enhances metastasis in mammary carcinomas of WAP-T mice.Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling HuR is necessary for mammary epithelial cell proliferation and polarity at least in part via ΔNp63.Cancer-specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis.Identification of a novel p53 target, COL17A1, that inhibits breast cancer cell migration and invasion Plakoglobin restores tumor suppressor activity of p53R175H mutant by sequestering the oncogenic potential of β-catenin.Mutations of p53 decrease sensitivity to the anthracycline treatments in bladder cancer cells.

P2860

Q24302433-81922616-E1A2-4C7C-8810-2B1F7E9EA030 Q24320050-5333FF8E-0A59-4427-B756-2C828CDAF503 Q26770576-A58B070E-78F6-4371-B2B7-F75A28B4174B Q26785448-EA32A005-F370-4A56-9B7C-DC4B81716E0D Q26825789-3BD35249-7497-4BD0-9263-BE9A8F048100 Q27333756-283A7EC0-E71D-45BC-B412-468155FEC7AB Q27686765-1C3EA110-823D-4150-BCA9-F803857B88DF Q30537354-C57A49AB-9A3E-47F2-8773-997889C226A1 Q33712095-D9DC0CFA-9142-467E-BB7F-CAC6F4D283E3 Q34785360-19326B8B-6FB7-4EB2-95FE-F11A05B06444 Q34917932-3656B984-20D2-4E64-880F-BC69374322AF Q35081210-CC3E880F-B9EA-4B41-8454-A98B3ED0ABFE Q35829871-E80E609B-15EB-4DC9-8D7F-78BF57325395 Q35909576-9306C291-9EC7-4263-8AAB-277AA0635BF4 Q35987262-CDE09647-E4E2-4019-85A7-A87CC86D2C68 Q36006937-F34AF7C0-9927-44E6-9AF4-E6EBCB48695A Q36070528-B5BAA0AE-FAE1-4905-85DC-7ABF1DB5BFAA Q36376097-A1000200-7703-46EB-BA02-52723C188472 Q36413546-3D683BD2-A25F-45C6-A777-69DF12D26F59 Q36677712-9731D5E1-39F6-4B2E-960E-CA9E4E8E3156 Q36998524-608F4E00-0614-4AFF-831A-B14011B3CB6D Q37336691-CA6DFEFD-C3C8-4138-8881-14A82A6F4B61 Q37419281-08EAABBB-BFBB-47E4-BFE7-2D6B4C962BBC Q37450854-8C285864-2D1D-466A-BAEC-96A2E093E3CE Q37625832-3A6B0173-ECF7-47B0-97E0-4B62A07EF7B4 Q37991651-C9144A83-5058-4214-98BA-7723D02AF991 Q38000940-2EB88103-0AB8-468E-A0B3-9D049981C3F4 Q38164308-8D922566-418A-4950-98A1-95BA8EAAA226 Q38197826-18D8C19F-763B-4396-89AE-5E6FC6063DB2 Q38218018-5477438B-CB39-4B40-9A8D-63F75A442769 Q38553239-2697B4AE-DB00-4A69-8133-798EE8828C16 Q38959098-5D8FDAE7-02EB-4B37-8E9F-014F9BD35C49 Q39080969-C4C2EB22-43EF-4DFC-A69C-AB69787A1188 Q39267423-AF8A8F42-F110-4B45-9BD0-D28CF09CCF15 Q39323166-0C1E8AEA-BFBB-41B4-BDF0-3C461A53676C Q41348871-870A5B11-A4AE-4B5A-BD79-58AFFB5BC0B1 Q55346775-03BB9BBA-EE14-43D9-9D4D-8437002E602E Q55504431-AA24E797-74B6-4895-9C5E-92E7E810AECD

P2860

Mutant p53 disrupts MCF-10A cell polarity in three-dimensional culture via epithelial-to-mesenchymal transitions.

http://www.wikidata.org/entity/Q34963520

description

2011 nî lūn-bûn

@nan

2011 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մարտին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@ast

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@en

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@nl

type

label

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@ast

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@en

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@nl

prefLabel

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@ast

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@en

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@nl

P1433

Q34963520-3A6B2191-3449-4EBC-8016-72D1160B15E9

P1476

Q34963520-A9220B3D-48BC-4535-891B-DF0DC8C7B01F

P2093

Q34963520-1E83D2F9-AD58-4097-9D2B-617EFB2A6B51

Q34963520-5D723542-FEF8-42E2-899B-EA8C13C8D34E

Q34963520-A43ACDFA-96E8-4B1F-992C-07F941724C23

P2860

Q34963520-02040A34-9A18-4788-8241-7BE4119C969C

Q34963520-0A560918-AF8F-430B-925C-DBA91C912A62

Q34963520-0D545BDC-41C5-470B-A501-9C226632FC02

Q34963520-146B59FD-DC8C-4CB9-95D5-8E25B7A3DC32

Q34963520-1CB6BD97-86A2-4813-8785-8C896B3448CA

Q34963520-221E6408-04CA-4E42-96A7-E3220A91308D

Q34963520-2C2AF37E-366B-4485-AE20-6A6B139F7A71

Q34963520-31C5D865-67C3-4755-9309-EC1766178A5B

Q34963520-36C5D387-F621-4E3E-9120-9DF1BC1CD9BF

Q34963520-37A66220-4D41-4BEB-AECF-C82D05CFCB4D

P304

Q34963520-568A0155-5068-4D2F-B9DE-50FA5278C5B8

P31

Q34963520-289F07A1-085A-4F42-A4DB-DA253FC565CD

P356

Q34963520-B2AEBA95-4977-471B-B40D-631776477D07

P407

Q34963520-8A9CA5A1-1A3B-41D9-A943-3464BA80B8BB

P433

Q34963520-33B55EB1-65B2-4747-BCD7-1A632C001B0A

P478

Q34963520-7DA1A3EC-F91D-4048-A52A-CAB1DFADF19F

P577

Q34963520-ED1A6092-E6D1-4E0F-9474-3567AEE2BCE2

P698

Q34963520-8AC59E65-1CA6-41AE-B03C-4E5A0664A144

P932

Q34963520-B6C8BC41-AD5E-4C97-A057-6A1C44CB6D9F

P356

JBC.M110.214585

P1433

Journal of Biological Chemistry

P1476

Mutant p53 disrupts MCF-10A ce ...... al-to-mesenchymal transitions.

@en

P2093

Wensheng Yan

http://www.w3.org/2001/XMLSchema#string

Xinbin Chen

http://www.w3.org/2001/XMLSchema#string

Yanhong Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

p53: puzzle and paradigm

Characterization of functional domains necessary for mutant p53 gain of function.

Cell polarity in eggs and epithelia: parallels and diversity.

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes.

p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

Database of p53 gene somatic mutations in human tumors and cell lines.

P304

16218-16228

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M110.214585

http://www.w3.org/2001/XMLSchema#string

P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

286

http://www.w3.org/2001/XMLSchema#string

P577

2011-03-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21454711

http://www.w3.org/2001/XMLSchema#string

P932

3091229

http://www.w3.org/2001/XMLSchema#string