about
Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Transcriptome profiling identifies genes and pathways deregulated upon floxuridine treatment in colorectal cancer cells harboring GOF mutant p53.Glucocorticoid receptor signalling activates YAP in breast cancer.Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer.Detection of cellular senescence within human invasive breast carcinomas distinguishes different breast tumor subtypes.Mutant p53 upregulates alpha-1 antitrypsin expression and promotes invasion in lung cancer.Targeting mutant p53 in cancer: a long road to precision therapy.Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner.Stathmin is overexpressed and regulated by mutant p53 in oral squamous cell carcinoma.A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis.Mutant p53-Nrf2 axis regulates the proteasome machinery in cancerMulti-omics reveals global effects of mutant p53 gain-of-function.Proteomic identification of ERP29 as a key chemoresistant factor activated by the aggregating p53 mutant Arg282Trp.Immunohistochemistry on IDH 1/2, ATRX, p53 and Ki-67 substitute molecular genetic testing and predict patient prognosis in grade III adult diffuse gliomas.Frequency of Somatic TP53 Mutations in Combination with Known Pathogenic Mutations in Colon Adenocarcinoma, Non-Small Cell Lung Carcinoma, and Gliomas as Identified by Next-Generation Sequencing.New therapeutic strategies to treat human cancers expressing mutant p53 proteins.TP53 in adult acute lymphoblastic leukemia.Analytic, Preanalytic, and Clinical Validation of p53 IHC for Detection of TP53 Missense Mutation in Prostate Cancer.Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma.Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.Mutant p53 tunes the NRF2-dependent antioxidant response to support survival of cancer cells.Complexes formed by mutant p53 and their roles in breast cancer.Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Mutant p53: One, No One, and One Hundred Thousand
@ast
Mutant p53: One, No One, and One Hundred Thousand
@en
Mutant p53: One, No One, and One Hundred Thousand
@nl
type
label
Mutant p53: One, No One, and One Hundred Thousand
@ast
Mutant p53: One, No One, and One Hundred Thousand
@en
Mutant p53: One, No One, and One Hundred Thousand
@nl
prefLabel
Mutant p53: One, No One, and One Hundred Thousand
@ast
Mutant p53: One, No One, and One Hundred Thousand
@en
Mutant p53: One, No One, and One Hundred Thousand
@nl
P2093
P2860
P50
P3181
P356
P1476
Mutant p53: One, No One, and One Hundred Thousand
@en
P2093
Dawid Walerych
Giannino Del Sal
Kamil Lisek
P2860
P3181
P356
10.3389/FONC.2015.00289
P407
P577
2015-12-21T00:00:00Z