Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis
about
DNA polymerase iota and related rad30-like enzymespoliota, a remarkably error-prone human DNA polymeraseConverting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C)Hypermutation in bacteria and other cellular systemsClusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequencesHuman DNA polymerase iota promiscuous mismatch extension.Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta.Genetic interactions between the Escherichia coli umuDC gene products and the beta processivity clamp of the replicative DNA polymerase.Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the beta processivity clampGenetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass.DNA damage control by novel DNA polymerases: translesion replication and mutagenesis.Lack of strand bias in UV-induced mutagenesis in Escherichia coliNascent DNA processing by RecJ favors lesion repair over translesion synthesis at arrested replication forks in Escherichia coli.Roles of YqjH and YqjW, homologs of the Escherichia coli UmuC/DinB or Y superfamily of DNA polymerases, in stationary-phase mutagenesis and UV-induced mutagenesis of Bacillus subtilis.A RecA protein surface required for activation of DNA polymerase V.Plasmid-encoded MucB protein is a DNA polymerase (pol RI) specialized for lesion bypass in the presence of MucA', RecA, and SSBDNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I.SOS mutator activity: unequal mutagenesis on leading and lagging strands.The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidanceSimple and efficient purification of Escherichia coli DNA polymerase V: cofactor requirements for optimal activity and processivity in vitro.Antibiotic resistance acquired through a DNA damage-inducible response in Acinetobacter baumannii.Mutations for Worse or Better: Low-Fidelity DNA Synthesis by SOS DNA Polymerase V Is a Tightly Regulated Double-Edged SwordCompetitive fitness during feast and famine: how SOS DNA polymerases influence physiology and evolution in Escherichia coliControlling mutation: intervening in evolution as a therapeutic strategy.Better living with hyper-mutation.Multiple strategies for translesion synthesis in bacteriaThe Lactococcus lactis plasmidome: much learnt, yet still lots to discover.Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells.Defining the position of the switches between replicative and bypass DNA polymerases.Repair of chromosomal abasic sites in vivo involves at least three different repair pathways.A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement.The Roles of UmuD in Regulating Mutagenesis.Plasmid-based lacZalpha assay for DNA polymerase fidelity: application to archaeal family-B DNA polymerase.Induction of the SOS response in starved Escherichia coli.DNA polymerase III from Escherichia coli cells expressing mutA mistranslator tRNA is error-prone.E. coli BW535, a triple mutant for the DNA repair genes xth, nth, and nfo, chronically induces the SOS response.RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.Replisome-mediated translesion synthesis by a cellular replicase.Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain.
P2860
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P2860
Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@ast
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@en
Highly mutagenic replication by DNA polymerase V
@nl
type
label
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@ast
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@en
Highly mutagenic replication by DNA polymerase V
@nl
prefLabel
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@ast
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@en
Highly mutagenic replication by DNA polymerase V
@nl
P2093
P2860
P356
P1476
Highly mutagenic replication b ...... for SOS untargeted mutagenesis
@en
P2093
A Maor-Shoshani
N B Reuven
P2860
P304
P356
10.1073/PNAS.97.2.565
P407
P577
2000-01-01T00:00:00Z