RecA acts in trans to allow replication of damaged DNA by DNA polymerase V. - Wikidata - awgldk - TriplyDB

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

http://www.wikidata.org/entity/Q46457518

about

A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V Insights into the complex levels of regulation imposed on Escherichia coli DNA polymerase V Regulation of Mutagenic DNA Polymerase V Activation in Space and Time Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V Cleavage of bacteriophage lambda cI repressor involves the RecA C-terminal domain.A novel role for RecA under non-stress: promotion of swarming motility in Escherichia coli K-12.Coordinating DNA polymerase traffic during high and low fidelity synthesis.The discovery of error-prone DNA polymerase V and its unique regulation by RecA and ATP Action of nitroheterocyclic drugs against Clostridium difficile.Translesion DNA polymerases Translesion DNA synthesis and mutagenesis in prokaryotes.Recombination and replication.The expression of superoxide dismutase (SOD) and a putative ABC transporter permease is inversely correlated during biofilm formation in Listeria monocytogenes 4b G.Translesion DNA Synthesis.Phenotypic and genetic consequences of protein damage.Biochemical characterization of RecA variants that contribute to extreme resistance to ionizing radiation.A RecA protein surface required for activation of DNA polymerase V.What a difference a decade makes: insights into translesion DNA synthesis.Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival.Simple and efficient purification of Escherichia coli DNA polymerase V: cofactor requirements for optimal activity and processivity in vitro.Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products.Regulation of bacterial RecA protein function.Mutations for Worse or Better: Low-Fidelity DNA Synthesis by SOS DNA Polymerase V Is a Tightly Regulated Double-Edged Sword Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination.Controlling mutation: intervening in evolution as a therapeutic strategy.Better living with hyper-mutation.Steric gate variants of UmuC confer UV hypersensitivity on Escherichia coli.The active form of DNA polymerase V is UmuD'(2)C-RecA-ATP.Biochemical basis for the essential genetic requirements of RecA and the beta-clamp in Pol V activation.A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase.Multiple strategies for translesion synthesis in bacteria Regulation of interactions with sliding clamps during DNA replication and repair.DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase.A proposal: Source of single strand DNA that elicits the SOS response.Single-stranded DNA-binding protein recruits DNA polymerase V to primer termini on RecA-coated DNA.RecFOR proteins are essential for Pol V-mediated translesion synthesis and mutagenesis.Replisome Dynamics during Chromosome Duplication.Characterization of Escherichia coli UmuC active-site loops identifies variants that confer UV hypersensitivity.Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914.RecA stimulates AlkB-mediated direct repair of DNA adducts

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P2860

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

http://www.wikidata.org/entity/Q46457518

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

@wuu

2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

2006年學術文章

@zh-hant

name

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

@en

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

@nl

type

label

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

@en

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

@nl

prefLabel

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

@en

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.

@nl

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P1476

RecA acts in trans to allow replication of damaged DNA by DNA polymerase V

@en

P2093

Michael M Cox

http://www.w3.org/2001/XMLSchema#string

Myron F Goodman

http://www.w3.org/2001/XMLSchema#string

Roger Woodgate

http://www.w3.org/2001/XMLSchema#string

P2860

ATP-mediated conformational changes in the RecA filament

The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication.

A model for SOS-lesion-targeted mutations in Escherichia coli.

RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation

Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis.

Error-prone repair DNA polymerases in prokaryotes and eukaryotes.

Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis

UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

RecA protein of Escherichia coli has a third essential role in SOS mutator activity.

New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesis

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883-887

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scholarly article

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10.1038/NATURE05042

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7105

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442

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Katharina Schlacher

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2006-08-01T00:00:00Z

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6859598

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1025161082

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16929290

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