Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment
about
A small molecule SMAC mimic LBW242 potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cellsInducing death in tumor cells: roles of the inhibitor of apoptosis proteins.Inhibitor of apoptosis proteins as therapeutic targets in multiple myeloma.Smac mimetic SM-164 potentiates APO2L/TRAIL- and doxorubicin-mediated anticancer activity in human hepatocellular carcinoma cellsBeyond the androgen receptor: new approaches to treating metastatic prostate cancer. Report of the 2013 Prouts Neck Prostate Cancer MeetingTargeting survivin in cancer: novel drug development approaches.Apoptosis in cancer: from pathogenesis to treatment.On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics.USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathwaysGli2 silencing enhances TRAIL-induced apoptosis and reduces tumor growth in human hepatoma cells in vivoBlockade of inhibitors of apoptosis (IAPs) in combination with tumor-targeted delivery of tumor necrosis factor-α leads to synergistic antitumor activityX-linked inhibitor of apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis.Smac mimetics and innate immune stimuli synergize to promote tumor deathSmac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity.IAP antagonists sensitize murine osteosarcoma cells to killing by TNFαBreast cancer proteome takes more than two to tango on TRAIL: beat them at their own game.The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis.Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with Deregulation of Extrinsic and Intrinsic Cell Death Pathways.PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy.Loss of cellular inhibitor of apoptosis protein 2 reduces atherosclerosis in atherogenic apoE-/- C57BL/6 mice on high-fat diet.Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy.Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC.Inhibitors of apoptosis: clinical implications in cancer.
P2860
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P2860
Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@ast
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@en
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@nl
type
label
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@ast
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@en
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@nl
prefLabel
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@ast
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@en
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@nl
P2093
P2860
P1476
Therapeutic potential and mole ...... ith TRAIL for cancer treatment
@en
P2093
Adrian T Ting
Anita Bellail
Chunhai Hao
Donna McEachern
Haiying Sun
Jianfeng Lu
Jinhui Liao
Longchuan Bai
Meilan Liu
P2860
P304
P356
10.1158/1535-7163.MCT-10-0864
P577
2011-03-03T00:00:00Z