Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins.

Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins.

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http://www.wikidata.org/entity/Q34974784
A Simple Method for Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation of Key Principles from Heparin/Heparan Sulfate-Binding ProteinsA Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II.A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules.Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase.Estimating glycosaminoglycan-protein interaction affinity: water dominates the specific antithrombin-heparin interaction.Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity.Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains.So you think computational approaches to understanding glycosaminoglycan-protein interactions are too dry and too rigid? Think again!Glycosaminoglycan-Protein Interactions by Nuclear Magnetic Resonance (NMR) Spectroscopy
P2860

Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins.

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http://www.wikidata.org/entity/Q34974784
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2014 nî lūn-bûn
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2014年の論文
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
@nl
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
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Toward a robust computational ...... ecificity for target proteins.
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P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Toward a robust computational ...... ecificity for target proteins.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932