about
Transforming growth factor-β2 is sequestered in preterm human milk by chondroitin sulfate proteoglycansToward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins.Designing "high-affinity, high-specificity" glycosaminoglycan sequences through computerized modelingChemoenzymatically prepared heparan sulfate containing rare 2-O-sulfonated glucuronic acid residues.A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II.A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules.Heparin interaction with a receptor on hyperglycemic dividing cells prevents intracellular hyaluronan synthesis and autophagy responses in models of type 1 diabetes.2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity.Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics.Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains.So you think computational approaches to understanding glycosaminoglycan-protein interactions are too dry and too rigid? Think again!Perspective on computational simulations of glycosaminoglycansA synthetic glycosaminoglycan mimetic blocks HSV-1 infection in human iris stromal cellsRigorous Analysis of Free Solution Glycosaminoglycan Dynamics Using Simple, New ToolsMucoadhesive role of tamarind xyloglucan on inflammation attenuates ulcerative colitis
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P50
description
researcher ORCID ID = 0000-0002-2870-9164
@en
wetenschapper
@nl
name
Nehru Viji Sankaranarayanan
@ast
Nehru Viji Sankaranarayanan
@en
Nehru Viji Sankaranarayanan
@es
Nehru Viji Sankaranarayanan
@nl
type
label
Nehru Viji Sankaranarayanan
@ast
Nehru Viji Sankaranarayanan
@en
Nehru Viji Sankaranarayanan
@es
Nehru Viji Sankaranarayanan
@nl
prefLabel
Nehru Viji Sankaranarayanan
@ast
Nehru Viji Sankaranarayanan
@en
Nehru Viji Sankaranarayanan
@es
Nehru Viji Sankaranarayanan
@nl
P106
P31
P496
0000-0002-2870-9164