Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
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CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cellsCCN proteins: A centralized communication networkConnective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal developmentConnective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesisVitreous mediators in retinal hypoxic diseasesNovel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 geneAFAP1 Is a Novel Downstream Mediator of TGF-β1 for CCN2 Induction in OsteoblastsTrial by CCN2: a standardized test for fibroproliferative disease?Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factorConnective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overloadImmunohistochemical localization of connective tissue growth factor, transforming growth factor-beta1 and phosphorylated-smad2/3 in the developing periodontium of ratsArterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: a role for CTGFEts-1 is essential for connective tissue growth factor (CTGF/CCN2) induction by TGF-β1 in osteoblasts.Developmental disturbances in early life stage mortality (M74) of Baltic salmon fry as studied by changes in gene expression.Modulation of migration and Ca2+ signaling in retinal pigment epithelium cells by recombinant human CTGF.Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors.Thrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway.CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma.Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosisA mouse strain where basal connective tissue growth factor gene expression can be switched from low to high.CXCL12 induces connective tissue growth factor expression in human lung fibroblasts through the Rac1/ERK, JNK, and AP-1 pathways.IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cellsCCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins.Small interfering RNAs (siRNAs) targeting TGF-beta1 mRNA suppress asbestos-induced expression of TGF-beta1 and CTGF in fibroblasts.The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways.Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general populationPreventative effect of Astragalus flavescens on hepatic fibrosis in rats and its mechanism of action.Connective tissue growth factor and cardiac diastolic dysfunction: human data from the Taiwan diastolic heart failure registry and molecular basis by cellular and animal models.Dexamethasone induces connective tissue growth factor expression in renal tubular epithelial cells in a mouse strain-specific manner.Smad3 deficiency ameliorates experimental obliterative bronchiolitis in a heterotopic tracheal transplantation modelAdvanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway.Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expressionAberrant signaling pathways of the lung mesenchyme and their contributions to the pathogenesis of bronchopulmonary dysplasiaA novel integrin alpha5beta1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cellsConnective tissue metabolism and gingival overgrowth.Pioglitazone attenuates vascular fibrosis in spontaneously hypertensive ratsThe role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis.The roles of connective tissue growth factor in the development of anastomotic esophageal strictures.Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options.Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction.
P2860
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P2860
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@ast
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@en
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@nl
type
label
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@ast
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@en
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@nl
prefLabel
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@ast
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@en
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@nl
P2093
P1433
P1476
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
@en
P2093
Andrew Leask
Ingrid E Blom
Roel Goldschmeding
P304
P356
10.1016/S0945-053X(02)00055-0
P577
2002-10-01T00:00:00Z