Human immunodeficiency virus type 1 Env with an intersubunit disulfide bond engages coreceptors but requires bond reduction after engagement to induce fusion
about
Structural mechanism of trimeric HIV-1 envelope glycoprotein activationComprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodiesPolyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individualsEvolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common ThemeAllosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivityIsomerization of the intersubunit disulphide-bond in Env controls retrovirus fusion.The C108g epitope in the V2 domain of gp120 functions as a potent neutralization target when introduced into envelope proteins derived from human immunodeficiency virus type 1 primary isolates.Comparative analysis of the fusion efficiency elicited by the envelope glycoprotein V1-V5 regions derived from human immunodeficiency virus type 1 transmitted perinatally.Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1Regulation of human immunodeficiency virus type 1 envelope glycoprotein fusion by a membrane-interactive domain in the gp41 cytoplasmic tail.Time-resolved imaging of HIV-1 Env-mediated lipid and content mixing between a single virion and cell membrane.Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.Variations in the Biological Functions of HIV-1 Clade C Envelope in a SHIV-Infected Rhesus Macaque during Disease Progression.Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirionsEnzyme digests eliminate nonfunctional Env from HIV-1 particle surfaces, leaving native Env trimers intact and viral infectivity unaffected.Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer.Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor bindingA comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.Peptide mimic of the HIV envelope gp120-gp41 interfaceForced virus evolution reveals functional crosstalk between the disulfide bonded region and membrane proximal ectodomain region of HIV-1 gp41Inhibition of the HIV-1 spike by single-PG9/16-antibody binding suggests a coordinated-activation model for its three protomeric unitsProfiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.Characterizing anti-HIV monoclonal antibodies and immune sera by defining the mechanism of neutralization.Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein.Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm.The cytoplasmic tail slows the folding of human immunodeficiency virus type 1 Env from a late prebundle configuration into the six-helix bundle.HIV envelope: challenges and opportunities for development of entry inhibitors.Escape from human immunodeficiency virus type 1 (HIV-1) entry inhibitors.Resistance of human immunodeficiency virus type 1 to a third-generation fusion inhibitor requires multiple mutations in gp41 and is accompanied by a dramatic loss of gp41 functionFunctional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41.Membrane-anchored inhibitory peptides capture human immunodeficiency virus type 1 gp41 conformations that engage the target membrane prior to fusion.Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusionAlanine scanning mutants of the HIV gp41 loop.The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment.Adding an Artificial Tail-Anchor to a Peptide-Based HIV-1 Fusion Inhibitor for Improvement of Its Potency and Resistance Profile.
P2860
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P2860
Human immunodeficiency virus type 1 Env with an intersubunit disulfide bond engages coreceptors but requires bond reduction after engagement to induce fusion
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Human immunodeficiency virus t ...... er engagement to induce fusion
@ast
Human immunodeficiency virus t ...... er engagement to induce fusion
@en
Human immunodeficiency virus t ...... er engagement to induce fusion
@nl
type
label
Human immunodeficiency virus t ...... er engagement to induce fusion
@ast
Human immunodeficiency virus t ...... er engagement to induce fusion
@en
Human immunodeficiency virus t ...... er engagement to induce fusion
@nl
prefLabel
Human immunodeficiency virus t ...... er engagement to induce fusion
@ast
Human immunodeficiency virus t ...... er engagement to induce fusion
@en
Human immunodeficiency virus t ...... er engagement to induce fusion
@nl
P2093
P2860
P1433
P1476
Human immunodeficiency virus t ...... er engagement to induce fusion
@en
P2093
G B Melikyan
L G Abrahamyan
R M Markosyan
P2860
P304
P356
10.1128/JVI.77.10.5829-5836.2003
P407
P577
2003-05-01T00:00:00Z