about
DNA Repair and Cytokines: TGF-β, IL-6, and Thrombopoietin as Different Biomarkers of RadioresistanceContribution of sleep to the repair of neuronal DNA double-strand breaks: evidence from flies and mice.BRCA1-deficient breast cancer cell lines are resistant to MEK inhibitors and show distinct sensitivities to 6-thioguanineCHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6.Intricate Macrophage-Colorectal Cancer Cell Communication in Response to Radiation.DEK is required for homologous recombination repair of DNA breaks.DNA damage response in cisplatin-induced nephrotoxicity.RECQL: a new breast cancer susceptibility gene.Novel method for the high-throughput production of phosphorylation site-specific monoclonal antibodies.Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissues.Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine.p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?Tuberatolide B Suppresses Cancer Progression by Promoting ROS-Mediated Inhibition of STAT3 Signaling.Keratin gene mutations influence the keratinocyte response to DNA damage and cytokine induced apoptosis.Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma.CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage.DNA damage response in nephrotoxic and ischemic kidney injury.Prophase I: Preparing Chromosomes for Segregation in the Developing Oocyte.The DNA damage response pathway in normal hematopoiesis and malignancies.Deficiency in DNA damage response, a new characteristic of cells infected with latent HIV-1.P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatmentComputational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential.Phosphorylation of PP1 Regulator Sds22 by PLK1 Ensures Accurate Chromosome Segregation.Analysis of centrosome and DNA damage response in PLK4 associated Seckel syndrome.HF-Free Boc Synthesis of Peptide Thioesters for Ligation and CyclizationCHK2 stability is regulated by the E3 ubiquitin ligase SIAH2.DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway.6-Gingerol prevents MEHP-induced DNA damage in human umbilical vein endothelia cells.The Role of MDM2 in Promoting Genome Stability versus Instability.Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition.Microtubule-targeting agents can sensitize cancer cells to ionizing radiation by an interphase-based mechanism.5,6,7,3',4',5'-Hexamethoxyflavone inhibits growth of triple-negative breast cancer cells via suppression of MAPK and Akt signaling pathways and arresting cell cycle.ATR/CHK1 inhibitors and cancer therapy.Directing the use of DDR kinase inhibitors in cancer treatment.Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors.Prexasertib, a cell cycle checkpoint kinases 1 and 2 inhibitor, increases in vitro toxicity of PARP inhibition by preventing Rad51 foci formation in BRCA wild type high-grade serous ovarian cancer.Checkpoint kinase 2 is dispensable for regulation of the p53 response but is required for G2/M arrest and cell survival in cells with p53 defects under heat stress.14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2.ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CHK2 kinase in the DNA damage response and beyond
@ast
CHK2 kinase in the DNA damage response and beyond
@en
CHK2 kinase in the DNA damage response and beyond
@nl
type
label
CHK2 kinase in the DNA damage response and beyond
@ast
CHK2 kinase in the DNA damage response and beyond
@en
CHK2 kinase in the DNA damage response and beyond
@nl
prefLabel
CHK2 kinase in the DNA damage response and beyond
@ast
CHK2 kinase in the DNA damage response and beyond
@en
CHK2 kinase in the DNA damage response and beyond
@nl
P2860
P921
P356
P1476
CHK2 kinase in the DNA damage response and beyond
@en
P2093
Domenico Delia
P2860
P304
P356
10.1093/JMCB/MJU045
P5008
P577
2014-11-17T00:00:00Z
2014-12-01T00:00:00Z