Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.
about
Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urateCommon variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibilityGenome-wide association analyses identify 18 new loci associated with serum urate concentrationsThe genetics of hyperuricaemia and goutThe multidrug transporter ABCG2: still more questions than answersUrate Handling in the Human BodyABC transporter research: going strong 40 years onRenal transport of uric acid: evolving concepts and uncertaintiesRole of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistanceThe role of drug transporters in the kidney: lessons from tenofovirMechanisms of mammalian iron homeostasisMechanistic insights into xanthine oxidoreductase from development studies of candidate drugs to treat hyperuricemia and goutABCG2: the molecular mechanisms of urate secretion and goutRegulatory pathways for ATP-binding cassette transport proteins in kidney proximal tubulesThe FLT3 inhibitor quizartinib inhibits ABCG2 at pharmacologically relevant concentrations, with implications for both chemosensitization and adverse drug interactionsJump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug TransporterThe Effect of Albumin on MRP2 and BCRP in the Vesicular Transport AssayExtra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary diseaseFructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review.Determinants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.The frequency of single nucleotide polymorphisms and their association with uric acid concentration based on data from genome-wide association studies in the Korean population.ProbABEL package for genome-wide association analysis of imputed data.Homozygous SLC2A9 mutations cause severe renal hypouricemia.Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosaABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approachesMetabolic syndrome, alcohol consumption and genetic factors are associated with serum uric acid concentrationAssociation of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk.The genetics of gout: towards personalised medicine?Functional polymorphisms of the ABCG2 gene are associated with gout disease in the Chinese Han male populationTargeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.Oral uricase eliminates blood uric acid in the hyperuricemic pig model.Replication of Gout/Urate Concentrations GWAS Susceptibility Loci Associated with Gout in a Han Chinese Population.Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population.Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.Uric acid transport and diseaseParacellular route is the major urate transport pathway across the blood-placental barrier
P2860
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P2860
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Identification of a urate tran ...... nal polymorphism causing gout.
@ast
Identification of a urate tran ...... nal polymorphism causing gout.
@en
Identification of a urate tran ...... nal polymorphism causing gout.
@nl
type
label
Identification of a urate tran ...... nal polymorphism causing gout.
@ast
Identification of a urate tran ...... nal polymorphism causing gout.
@en
Identification of a urate tran ...... nal polymorphism causing gout.
@nl
prefLabel
Identification of a urate tran ...... nal polymorphism causing gout.
@ast
Identification of a urate tran ...... nal polymorphism causing gout.
@en
Identification of a urate tran ...... nal polymorphism causing gout.
@nl
P2093
P2860
P50
P356
P1476
Identification of a urate tran ...... nal polymorphism causing gout.
@en
P2093
Michael Köttgen
Owen M Woodward
William B Guggino
P2860
P304
10338-10342
P356
10.1073/PNAS.0901249106
P407
P577
2009-06-08T00:00:00Z