Self and non-self discrimination of intracellular membranes by the innate immune system.
about
The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malariaLoss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteinsGalectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis.Ubiquitination of pathogen-containing vacuoles promotes host defense to Chlamydia trachomatis and Toxoplasma gondii.Interferon-inducible GTPases in cell autonomous and innate immunity.Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.Quo vadis? Interferon-inducible GTPases go to their target membranes via the LC3-conjugation system of autophagy.Targeting by AutophaGy proteins (TAG): Targeting of IFNG-inducible GTPases to membranes by the LC3 conjugation system of autophagy.Guanylate Binding Proteins regulate inflammasome activation in response to hyper-injected Yersinia translocon components.Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: roles in intracellular lysis of pathogens.Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.Plant Hormesis Management with Biostimulants of Biotic Origin in Agriculture.Sweet host revenge: Galectins and GBPs join forces at broken membranes.Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases.
P2860
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P2860
Self and non-self discrimination of intracellular membranes by the innate immune system.
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Self and non-self discrimination of intracellular membranes by the innate immune system.
@ast
Self and non-self discrimination of intracellular membranes by the innate immune system.
@en
Self and non-self discrimination of intracellular membranes by the innate immune system.
@nl
type
label
Self and non-self discrimination of intracellular membranes by the innate immune system.
@ast
Self and non-self discrimination of intracellular membranes by the innate immune system.
@en
Self and non-self discrimination of intracellular membranes by the innate immune system.
@nl
prefLabel
Self and non-self discrimination of intracellular membranes by the innate immune system.
@ast
Self and non-self discrimination of intracellular membranes by the innate immune system.
@en
Self and non-self discrimination of intracellular membranes by the innate immune system.
@nl
P2860
P1433
P1476
Self and non-self discrimination of intracellular membranes by the innate immune system.
@en
P2093
Jörn Coers
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003538
P50
P577
2013-09-19T00:00:00Z