Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism.
about
Adenovirus E1B 55-kilodalton oncoprotein binds to Daxx and eliminates enhancement of p53-dependent transcription by DaxxGoing viral: a review of replication-selective oncolytic adenovirusesAdenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cellsAdenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblastsThe human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.Export of adenoviral late mRNA from the nucleus requires the Nxf1/Tap export receptor.The repression domain of the E1B 55-kilodalton protein participates in countering interferon-induced inhibition of adenovirus replication.An activity associated with human chromosome 21 permits nuclear colocalization of the adenovirus E1B-55K and E4orf6 proteins and promotes viral late gene expression.Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53.Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export.The adenovirus L4 33-kilodalton protein binds to intragenic sequences of the major late promoter required for late phase-specific stimulation of transcription.Intranuclear targeting and nuclear export of the adenovirus E1B-55K protein are regulated by SUMO1 conjugation.Timely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival.Role of the RNA recognition motif of the E1B 55 kDa protein in the adenovirus type 5 infectious cycle.Inactivating intracellular antiviral responses during adenovirus infection.Reduced infectivity of adenovirus type 5 particles and degradation of entering viral genomes associated with incomplete processing of the preterminal protein.Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activityRUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesisAggresome formation by the adenoviral protein E1B55K is not conserved among adenovirus species and is not required for efficient degradation of nuclear substratesThe adenoviral E1B 55-kilodalton protein controls expression of immune response genes but not p53-dependent transcription.Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation.Extensive post-translational modification of active and inactivated forms of endogenous p53.A proteomic approach to identify candidate substrates of human adenovirus E4orf6-E1B55K and other viral cullin-based E3 ubiquitin ligases.Morphological, Biochemical, and Functional Study of Viral Replication Compartments Isolated from Adenovirus-Infected Cells.Functional cooperation between human adenovirus type 5 early region 4, open reading frame 6 protein, and cellular homeobox protein HoxB7.The human adenovirus type 5 E1B 55-kilodalton protein is phosphorylated by protein kinase CK2.CRM1-dependent transport supports cytoplasmic accumulation of adenoviral early transcripts.The E4orf6/E1B55K E3 ubiquitin ligase complexes of human adenoviruses exhibit heterogeneity in composition and substrate specificity.Proteasome-dependent degradation of Daxx by the viral E1B-55K protein in human adenovirus-infected cells.Adeno-associated virus small rep proteins are modified with at least two types of polyubiquitination.Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates.Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein.Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes.Automatic detection and measurement of viral replication compartments by ellipse adjustmentViral regulation of mRNA export.The E3 ubiquitin ligase activity associated with the adenoviral E1B-55K-E4orf6 complex does not require CRM1-dependent export.Nucleolin is required for RNA polymerase I transcription in vivo.A 49-kilodalton isoform of the adenovirus type 5 early region 1B 55-kilodalton protein is sufficient to support virus replication
P2860
Q24297809-6A190C4C-3FF4-4C1F-889E-42F01A548D25Q26797520-1C7A9DD3-27C8-4CFD-9F1D-C739AA9BDD9CQ28574947-E9A7CD0C-7E46-4129-A0E1-B64EE8903AE4Q34301861-FB45708F-A152-4EC2-9931-03AF896483F3Q34388476-3DF074C2-BB9B-4B04-A53D-ECCF61A377C7Q34529776-B26F5022-2375-4026-9B1C-DDBC118685D7Q34579032-9EFAF0CA-7FFF-4105-BD5C-A137FC35B053Q35105167-AAB2D3DB-BE5E-4A06-AEB1-B586EF716891Q35111076-0CF3D6EE-1F04-45FA-BAF6-E1C56DFCFDEAQ35634994-AD72F832-3333-454C-B76B-86C92A1C91F1Q35635286-B76A03B8-8E5A-4CAA-AEF2-D4FDCB0A8019Q35800318-C0FD5B2F-80E5-4DAE-B5EE-598E9CB1DC86Q35826320-1B4ABD9C-2921-41AA-B92F-94A66FAE9386Q35850341-D38880DB-DC7B-4EFF-9FD4-CF5575958EB0Q36039006-D016DE89-7040-4841-A3DE-A5EB61875E72Q36318156-C17D7F05-88DE-4D9C-B8B2-77E13157F918Q36414237-6489D5BA-3F11-4AEB-A0E0-925AA90D0B43Q36484050-2460BFFA-3F33-4FE6-B81A-29EBB7162FBDQ36747955-6EFCDF95-B301-4CD6-9E02-1723547C847AQ36759991-5C4751DD-BBA2-4FB7-AB76-28B4AFF5B1EFQ37145192-C2919EC0-295F-4CE8-AF2E-31C18B87050CQ37391112-F6C58134-B6FE-4F61-A00D-D5CD0940F14EQ37428803-2DDA645A-A755-4A47-9FA5-0250C6412FF5Q37451972-4D637D62-9719-465A-9C70-82209B2E3176Q38803897-A7E74952-D140-4A7E-8107-226A672E24B0Q39354514-BA46E658-050E-439F-A6F2-EC5BAA1A25D0Q39424095-F6B5977E-1117-436C-9216-5CD50E008941Q39428215-4C4824D5-9E03-466C-9A1D-C1B6D8E2C71EQ39633445-94CF038E-49AB-4E1E-9F96-0CBF00D3FF53Q39702317-70E70F90-7FDB-42AB-B20F-56A70F797A72Q39778963-206A6D66-8F1D-4FE5-A80B-8AE9EBCCD5C2Q39963290-F81BF899-2425-45C4-AE7E-102AA01038EEQ40018751-D7D307DA-6EF3-47CC-AE24-D59BD3B9BC52Q40353337-5D51CEAC-6F09-4877-8962-7DA66C5A1A6DQ40384561-D4CC6525-7B11-439F-A771-D575DEA07A2EQ40461601-D0697A03-11D6-42D3-9CDF-3C492A95D194Q40763108-F1ABBB3A-B04A-4D03-9B4A-BFDC81AA415BQ41897865-704B196B-8143-4BAA-9470-6C0C655054D8Q42083099-658508CF-4862-465B-BDA3-E3F03C4139B2Q42090834-E0D8058D-124C-4B91-A9EA-E7AF1A48338D
P2860
Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@ast
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@en
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@nl
type
label
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@ast
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@en
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@nl
prefLabel
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@ast
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@en
Effects of mutations in the ad ...... on viral late mRNA metabolism.
@nl
P2860
P1433
P1476
Effects of mutations in the ad ...... on viral late mRNA metabolism
@en
P2093
P2860
P304
P356
10.1128/JVI.76.9.4507-4519.2002
P407
P50
P577
2002-05-01T00:00:00Z