A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics - Wikidata - awgldk - TriplyDB

A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics

A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics

http://www.wikidata.org/entity/Q35005041

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Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay The hnRNP family: insights into their role in health and disease Post-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulation A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA Identification of a signature motif in target mRNAs of RNA-binding protein AUF1 Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1.Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements Alternatively expressed domains of AU-rich element RNA-binding protein 1 (AUF1) regulate RNA-binding affinity, RNA-induced protein oligomerization, and the local conformation of bound RNA ligands.Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.Different modes of interaction by TIAR and HuR with target RNA and DNA Substrate dependence of conformational changes in the RNA-binding domain of tristetraprolin assessed by fluorescence spectroscopy of tryptophan mutants.Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences.Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements.LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner.Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1 mRNA stability control: a clandestine force in normal and malignant hematopoiesis.mRNA stability and cancer: an emerging link?Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence.Assembly of functional ribonucleoprotein complexes by AU-rich element RNA-binding protein 1 (AUF1) requires base-dependent and -independent RNA contacts.RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting.Site-specific variations in RNA folding thermodynamics visualized by 2-aminopurine fluorescence.The 3'-untranslated region length and AU-rich RNA location modulate RNA-protein interaction and translational control of β2-adrenergic receptor mRNA.Impact of RNA structure on ZFP36L2 interaction with luteinizing hormone receptor mRNA.AUF1 regulation of coding and noncoding RNA.Post-transcriptional regulation of cytokine and growth factor signaling in cancer.mRNA degradation plays a significant role in the program of gene expression regulated by phosphatidylinositol 3-kinase signaling.The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis.FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1.Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.LARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protection FasL expression in activated T lymphocytes involves HuR-mediated stabilization.The human c-fos and TNFalpha AU-rich elements show different effects on mRNA abundance and protein expression depending on the reporter in the yeast Pichia pastoris.Pin1: a proline isomerase that makes you wheeze?Estradiol up-regulates AUF1p45 binding to stabilizing regions within the 3'-untranslated region of estrogen receptor alpha mRNA.RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate.Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions.

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P2860

A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics

http://www.wikidata.org/entity/Q35005041

description

2005 nî lūn-bûn

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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type

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A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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prefLabel

A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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Journal of Biological Chemistry

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A hairpin-like structure withi ...... tivity and mRNA decay kinetics

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P2093

Brandy Y Brewer

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Bridget P Keenan

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Elizabeth J Fialcowitz

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Gerald M Wilson

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P2860

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

Mfold web server for nucleic acid folding and hybridization prediction

Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

Structural basis for recognition of AU-rich element RNA by the HuD protein

Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

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22406-22417

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10.1074/JBC.M500618200

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23

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280

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15809297

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1553220

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