An unexpected role for TASK-3 potassium channels in network oscillations with implications for sleep mechanisms and anesthetic action.
about
Control of sleep and wakefulnessTASK channels contribute to neuroprotective action of inhalational anesthetics.TASK Channels on Basal Forebrain Cholinergic Neurons Modulate Electrocortical Signatures of Arousal by HistamineSound Pressure Levels in 2 Veterinary Intensive Care Units.TASK-3 as a potential antidepressant target.Staying awake--a genetic region that hinders α2 adrenergic receptor agonist-induced sleep.Rapid developmental maturation of neocortical FS cell intrinsic excitability.Motoneuronal TASK channels contribute to immobilizing effects of inhalational general anestheticsInduced changes in protein receptors conferring resistance to anesthetics.Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current.Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.The role of linear and voltage-dependent ionic currents in the generation of slow wave oscillations.Altered activity in the central medial thalamus precedes changes in the neocortex during transitions into both sleep and propofol anesthesia.Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept.Molecular modeling of a tandem two pore domain potassium channel reveals a putative binding site for general anesthetics.Covalent modification of a volatile anesthetic regulatory site activates TASK-3 (KCNK9) tandem-pore potassium channels.Breathing Stimulant Compounds Inhibit TASK-3 Potassium Channel Function Likely by Binding at a Common Site in the Channel Pore.GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousnessStrain differences in cortical electroencephalogram associated with isoflurane-induced loss of consciousness.TASK-1 (KCNK3) and TASK-3 (KCNK9) tandem pore potassium channel antagonists stimulate breathing in isoflurane-anesthetized rats.New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain.Molecular physiology of pH-sensitive background K(2P) channels.NALCN: a regulator of pacemaker activity.Mammalian sleep genetics.The role of K₂p channels in anaesthesia and sleep.Much more than a leak: structure and function of K₂p-channels.Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina.Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.Optical reversal of halothane-induced immobility in C. elegans.An extracellular ion pathway plays a central role in the cooperative gating of a K(2P) K+ channel by extracellular pH.Halogenated Ether, Alcohol, and Alkane Anesthetics Activate TASK-3 Tandem Pore Potassium Channels Likely through a Common Mechanism.A balance of outward and linear inward ionic currents is required for generation of slow-wave oscillations.High sensitivity of spontaneous spike frequency to sodium leak current in a Lymnaea pacemaker neuron.Discovery of a pharmacologically active antagonist of the two-pore-domain potassium channel K2P9.1 (TASK-3).Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation.Epileptiform activity during inert gas euthanasia of mice.
P2860
Q24634619-CD6A1886-6C4A-4E0B-ACE2-A3403F0EEC68Q30253001-E2AB9FE9-2DFC-462B-A5A6-7775E73113CBQ30278556-D3A9ACD6-6A06-460F-8C7D-3629488786BFQ30381031-A77A7721-CD56-45E0-914C-B4E609FF64F6Q30424610-F2D0BA0D-16AC-457F-AEA4-03DCC5E65331Q30425810-7E5D4C2F-8BFE-4034-AAF8-BDD422BEA098Q30428037-F093EEB8-21F5-48DC-A9FF-8F313431C562Q30433922-7DCBF61A-51D8-4CDD-92CE-698A3073058EQ33726563-3FB5B379-8245-4737-8CD7-4DD1E8DC4ED9Q33878235-A4B193EA-9EAD-4E5F-BDDF-763B86FF387CQ33981739-662FC9C8-0C7B-40A8-AF15-AC0ABE63692CQ34167578-5A1A7B5E-7775-455F-8BC5-5FBBA80FF0A2Q34268942-482F01BC-07A3-4E85-B331-6BE1A913FA49Q34994509-66A6AF99-C248-40FE-B3A1-C8775EF60B02Q35013347-801D8DFD-8DA6-4BC5-9AB0-4B01782FD0A6Q35776793-A39A1289-0430-4E9A-A5D0-2A2FF45AB371Q36186112-60D4D3FE-E511-479E-898D-731DB26DD0F8Q36302879-CE715480-373D-4FF7-BB9E-9FC3DFD9B6DCQ37103954-66097B25-1B15-4068-84C7-A824D272A894Q37398806-75EE4F21-716C-481E-83FB-2548C06173CAQ37445958-3F404AB4-5CAF-4AA7-9818-0577E0DAE82AQ37968582-71E855C7-9B91-4236-A2F0-E14B71259CAAQ38000093-E3698F95-1411-4708-B0BE-2227747C530AQ38043400-E3276E38-4809-42B8-8AC9-9CF5BDE65F55Q38284420-2E0825E5-CD23-4E0E-BFDC-3149B2D28716Q38384425-441761BA-377C-4F4A-89FF-48C46E0FC0D1Q38819603-99AE04DA-9BF9-4198-8C85-8A1CED592CBAQ39216998-B5CAB4DE-FA2C-47CA-A61D-78215D06D923Q39987996-285FEDAC-025F-4BE8-9205-530AD6B2A8C3Q43240562-639C74EC-4638-445A-8E85-C7FB698405F8Q47316987-ABA1D441-A8C3-42E8-A962-0A11DE84B1B9Q47833197-4704FE0A-8258-4601-9F52-4C336F0B3F62Q47853782-B5AC09CD-0055-429A-91BE-AFC4597BE426Q48283087-C6EAA5B9-3730-42AF-9F1C-3B9D1FA46E4BQ49343653-B34CD2DA-FE4E-4094-AE0B-98F8C70A8D28Q54984969-02765B8F-8B59-451A-A6B6-1A55D4005C55
P2860
An unexpected role for TASK-3 potassium channels in network oscillations with implications for sleep mechanisms and anesthetic action.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@ast
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@en
type
label
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@ast
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@en
prefLabel
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@ast
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@en
P2093
P2860
P50
P356
P1476
An unexpected role for TASK-3 ...... hanisms and anesthetic action.
@en
P2093
Alex Caley
Anna Y Zecharia
Christian J Robledo
Daniel S J Pang
David R Carr
P2860
P304
17546-17551
P356
10.1073/PNAS.0907228106
P407
P577
2009-09-24T00:00:00Z