Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. - Wikidata - awgldk - TriplyDB

Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies.

Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies.

http://www.wikidata.org/entity/Q35006687

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Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome Aberrant insulin signaling in Alzheimer's disease: current knowledge Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive Potential Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer's Disease Biomarkers: A Pilot Clinical Trial.Insulin resistance in Alzheimer's disease.Abdominal Obesity and Brain Atrophy in Type 2 Diabetes Mellitus.The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice.Changes in insulin and insulin signaling in Alzheimer's disease: cause or consequence?The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-β in Young and Old APP/PS1 Mice.Potential Neuroprotective Effects of Adiponectin in Alzheimer's Disease.The Role of TDP-43 in Alzheimer's Disease.Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.Tau deletion promotes brain insulin resistance A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology.Effects of Exercise on Type 2 Diabetes Mellitus-Related Cognitive Impairment and Dementia.Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.The diabetic brain and cognition.Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal Neurons Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons.Insulin Receptor Isoforms in Physiology and Disease: An Updated View.Rat brain glucose transporter-2, insulin receptor and glial expression are acute targets of intracerebroventricular streptozotocin: risk factors for sporadic Alzheimer's disease?The Implication of the Brain Insulin Receptor in Late Onset Alzheimer's Disease Dementia.Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums.Regulation of brain insulin signaling: A new function for tau.Insulin resistance and exendin-4 treatment for multiple system atrophy.Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice.Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism.Relationship of Type 2 Diabetes to Human Brain Pathology.Apomorphine Therapy for Neuronal Insulin Resistance in a Mouse Model of Alzheimer's Disease.Insulin Resistance as a Therapeutic Target in the Treatment of Alzheimer's Disease: A State-of-the-Art Review.Altered Insulin/Insulin-Like Growth Factor Signaling in a Comorbid Rat model of Ischemia and β-Amyloid Toxicity.Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.Therapeutic implications of how TNF links APOE, P-tau, α-synuclein, β-amyloid, and insulin resistance in neurodegenerative diseases Using Multi-Scale Genetic, Neuroimaging and Clinical Data for Predicting Alzheimer's Disease and Reconstruction of Relevant Biological Mechanisms

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P2860

Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies.

http://www.wikidata.org/entity/Q35006687

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年学术文章

@wuu

2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

@zh-sg

2014年學術文章

@yue

name

Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

@ast

Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

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type

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Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

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Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

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prefLabel

Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

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Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

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S00401-014-1328-5

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Acta Neuropathologica

P1476

Abnormal serine phosphorylatio ...... mer's disease and tauopathies.

@en

P2093

Edward B Lee

http://www.w3.org/2001/XMLSchema#string

Hala Kazi

http://www.w3.org/2001/XMLSchema#string

Jon B Toledo

http://www.w3.org/2001/XMLSchema#string

Li-Ying Han

http://www.w3.org/2001/XMLSchema#string

Mark Yarchoan

http://www.w3.org/2001/XMLSchema#string

Natalia Louneva

http://www.w3.org/2001/XMLSchema#string

Sangwon F Kim

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Virginia M-Y Lee

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Zoe Arvanitakis

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P2860

Parkinson's disease, insulin resistance and novel agents of neuroprotection

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain

Banting lecture 1988. Role of insulin resistance in human disease

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

A central role for JNK in obesity and insulin resistance

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

The glamour and gloom of glycogen synthase kinase-3

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s00401-014-1328-5

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10.1007/S00401-014-1328-5

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5

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128

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John Q. Trojanowski

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2014-08-09T00:00:00Z

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25107476

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Alzheimer's disease

phosphorylation

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4304658

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