Kif15 cooperates with eg5 to promote bipolar spindle assembly.
about
Kinesin-5: cross-bridging mechanism to targeted clinical therapyPlk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.Regulation of localization and activity of the microtubule depolymerase MCAKThe transition from meiotic to mitotic spindle assembly is gradual during early mammalian developmentKinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching.TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleHitting the brakes: targeting microtubule motors in cancerIdentification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells.S. pombe kinesins-8 promote both nucleation and catastrophe of microtubulesKLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly.Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module.Kinesin-12 motors cooperate to suppress microtubule catastrophes and drive the formation of parallel microtubule bundles.The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal developmentMicrotubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control.Recent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapySelective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signalingCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisNuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.Kinesin-12 differentially affects spindle assembly depending on its microtubule substrateKif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube.EGF-induced centrosome separation promotes mitotic progression and cell survival.Endogenous localizome identifies 43 mitotic kinesins in a plant cellCaenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1.Kinetochore-microtubule stability governs the metaphase requirement for Eg5.Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanismPicropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanismAssembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1Kinesin-5 Contributes to Spindle-length Scaling in the Evolution of Cancer toward MetastasisKinesin-5 inhibitor resistance is driven by kinesin-12Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast.Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics.Loss-of-Function Mutations in KIF15 Underlying a Braddock-Carey Genocopy.MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes.Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeastCyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.The kinesin-13 KLP10A motor regulates oocyte spindle length and affects EB1 binding without altering microtubule growth ratesChromokinesins: localization-dependent functions and regulation during cell division.MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment.ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.
P2860
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P2860
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@ast
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@en
type
label
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@ast
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@en
prefLabel
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@ast
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@en
P2093
P1433
P1476
Kif15 cooperates with eg5 to promote bipolar spindle assembly.
@en
P2093
Erica F Geers
Libor Macůrek
Marvin E Tanenbaum
Mónica Alvarez-Fernández
P304
P356
10.1016/J.CUB.2009.08.027
P407
P577
2009-10-08T00:00:00Z