EGF-induced centrosome separation promotes mitotic progression and cell survival.
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Regulation of the centrosome cycleHitting the brakes: targeting microtubule motors in cancerThe bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stabilityThe tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle.Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunctionMechanisms promoting escape from mitotic stress-induced tumor cell death.The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes.Effect of EGFR and p-AKT Overexpression on Chromosomal Instability in Gastric Cancer.Chronic Exposure to Particulate Chromate Induces Premature Centrosome Separation and Centriole Disengagement in Human Lung Cells.Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16.Mitotic kinase cascades orchestrating timely disjunction and movement of centrosomes maintain chromosomal stability and prevent cancer.G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation.Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity.Separate to operate: control of centrosome positioning and separation.Centrosomes in spindle organization and chromosome segregation: a mechanistic view.Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.Tyr(less) kinase signaling during mitosis.Orchestrating cellular signaling pathways-the cellular "conductor" protein tyrosine phosphatase interacting protein 51 (PTPIP51).DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets.Centrosomes at M phase act as a scaffold for the accumulation of intracellular ubiquitinated proteins.Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1).Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistanceTumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic AgentsMitotic Regulation by NEK Kinase Networks.ErbB Receptors and Cancer.STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles.Cell Cycle Synchronization of HeLa Cells to Assay EGFR Pathway Activation.Stable centrosomal roots disentangle to allow interphase centriole independence.The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes.
P2860
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P2860
EGF-induced centrosome separation promotes mitotic progression and cell survival.
description
2013 nî lūn-bûn
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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2013 թվականի մայիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@ast
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@en
type
label
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@ast
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@en
prefLabel
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@ast
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@en
P2093
P2860
P1433
P1476
EGF-induced centrosome separation promotes mitotic progression and cell survival.
@en
P2093
Alwin Krämer
Andrew M Fry
Elmar Schiebel
Marco R Cosenza
Mayumi Isokane
P2860
P304
P356
10.1016/J.DEVCEL.2013.03.012
P407
P577
2013-05-02T00:00:00Z