The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
about
Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunctionKinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching.TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleIdentification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells.KLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly.Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module.Kinesin-12 motors cooperate to suppress microtubule catastrophes and drive the formation of parallel microtubule bundles.The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal developmentRecent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapyKi-67 acts as a biological surfactant to disperse mitotic chromosomesCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisDynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2.Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.Kinesin-12 differentially affects spindle assembly depending on its microtubule substrateEGF-induced centrosome separation promotes mitotic progression and cell survival.Endogenous localizome identifies 43 mitotic kinesins in a plant cellCaenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1.Kinetochore-microtubule stability governs the metaphase requirement for Eg5.Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanismAssembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1Kinesin-5 inhibitor resistance is driven by kinesin-12Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics.Loss-of-Function Mutations in KIF15 Underlying a Braddock-Carey Genocopy.Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery.TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts.Chromokinesins: localization-dependent functions and regulation during cell division.Interaction of NuMA protein with the kinesin Eg5: its possible role in bipolar spindle assembly and chromosome alignment.Kinesin-12 influences axonal growth during zebrafish neural developmentNuclear location of tumor suppressor protein maspin inhibits proliferation of breast cancer cells without affecting proliferation of normal epithelial cells.The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes.The centrosome and bipolar spindle assembly: does one have anything to do with the other?Systematic dissection of dynein regulators in mitosisMitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2.Suppression of microtubule assembly kinetics by the mitotic protein TPX2.Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains.Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.Metaphase Spindle Assembly.Mitosis as an anti-cancer target.The molecular basis for kinesin functional specificity during mitosis.TPX2: of spindle assembly, DNA damage response, and cancer.
P2860
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P2860
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@ast
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@en
type
label
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@ast
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@en
prefLabel
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@ast
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@en
P2093
P1433
P1476
The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.
@en
P2093
David Vanneste
Masatoshi Takagi
Naoko Imamoto
P304
P356
10.1016/J.CUB.2009.09.019
P407
P577
2009-10-08T00:00:00Z