Bioengineered human arginase I with enhanced activity and stability controls hepatocellular and pancreatic carcinoma xenografts.

Bioengineered human arginase I with enhanced activity and stability controls hepatocellular and pancreatic carcinoma xenografts.

Item
http://www.wikidata.org/entity/Q35015474
Arginine deprivation therapy for malignant melanomaTargeting amino acid metabolism in cancer growth and anti-tumor immune responseBinding of the unreactive substrate analogL-2-amino-3-guanidinopropionic acid (dinor-L-arginine) to human arginase IAmino acid deprivation using enzymes as a targeted therapy for cancer and viral infectionsSCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis.Arginase in retinopathy.Recombinant human arginase toxicity in mice is reduced by citrulline supplementationStrategies for optimizing the serum persistence of engineered human arginase I for cancer therapy.Microarray profiling shows distinct differences between primary tumors and commonly used preclinical models in hepatocellular carcinoma.Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cellsTargeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges.Drug-induced amino acid deprivation as strategy for cancer therapy.Arginine dependence of tumor cells: targeting a chink in cancer's armor.IL-10 and ARG-1 concentrations in bone marrow and peripheral blood of metastatic neuroblastoma patients do not associate with clinical outcome.Effects of the combined arginase and canavanine treatment on leukemic cells in vitro and in vivo.Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells.
P2860

Bioengineered human arginase I with enhanced activity and stability controls hepatocellular and pancreatic carcinoma xenografts.

Item
http://www.wikidata.org/entity/Q35015474
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Bioengineered human arginase I ...... ncreatic carcinoma xenografts.
@ast
Bioengineered human arginase I ...... ncreatic carcinoma xenografts.
@en
type
label
Bioengineered human arginase I ...... ncreatic carcinoma xenografts.
@ast
Bioengineered human arginase I ...... ncreatic carcinoma xenografts.
@en
prefLabel
Bioengineered human arginase I ...... ncreatic carcinoma xenografts.
@ast
Bioengineered human arginase I ...... ncreatic carcinoma xenografts.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Bioengineered human arginase I ...... ancreatic carcinoma xenografts
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932