Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells.
about
In search of druggable targets for GBM amino acid metabolism.Drug-induced amino acid deprivation as strategy for cancer therapy.Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase.Arginine dependence of tumor cells: targeting a chink in cancer's armor.The interplay between metabolic remodeling and immune regulation in glioblastoma.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.Elucidating immunometabolic targets in glioblastoma.Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells.Low expressions of ASS1 and OTC in glioblastoma suggest the potential clinical use of recombinant human arginase (rhArg).
P2860
Q36293108-CB0468C4-3963-4FD9-8276-A19BAB104836Q38657061-F4FB5DB6-C22C-4303-BA71-D24A16CBB2B4Q38813861-E1DDA78B-AFDE-4DC6-AB7A-59DED2CA9D48Q38816145-B500B660-FFF6-4336-941D-7C3CE3C6A16BQ39328710-AC4DC28A-DAB6-4932-BC67-753353EA54D5Q42362675-3388B0DD-CA2B-46F5-8608-18DD6A614722Q46664541-84398DEE-F577-43E3-A5B4-59D5190C4279Q50981834-15C7C476-D9E8-4024-9B0A-CE781513F048Q53064344-F89985A5-5140-4EFA-A5C2-EEED2B3E3E2E
P2860
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh-hant
name
Human recombinant arginase I ( ...... c to human glioblastoma cells.
@en
Human recombinant arginase I
@nl
type
label
Human recombinant arginase I ( ...... c to human glioblastoma cells.
@en
Human recombinant arginase I
@nl
prefLabel
Human recombinant arginase I ( ...... c to human glioblastoma cells.
@en
Human recombinant arginase I
@nl
P2093
P2860
P1476
Human recombinant arginase I ( ...... c to human glioblastoma cells.
@en
P2093
Everett Stone
Mirvat El-Sibai
Noura Ghazale
Oula Khoury
Ralph J Abi-Habib
P2860
P2888
P356
10.1007/S11060-014-1698-5
P577
2015-01-08T00:00:00Z