Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
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Structure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric IntermediateVariations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamilyAldehyde Decarbonylases: Enigmatic Enzymes of Hydrocarbon BiosynthesisMechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymesMonooxygenation of an aromatic ring by F43W/H64D/V68I myoglobin mutant and hydrogen peroxide. Myoglobin mutants as a model for P450 hydroxylation chemistry.Kinetics of oxidation of benzphetamine by compounds I of cytochrome P450 2B4 and its mutants.Quantitative production of compound I from a cytochrome P450 enzyme at low temperatures. Kinetics, activation parameters, and kinetic isotope effects for oxidation of benzyl alcohol.Enhanced catalytic activity and unexpected products from the oxidation of cyclohexene by organic nanoparticles of 5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)porphyrinatoiron(III) in water by using O2.Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates H(peroxo) and Q proceed by distinct mechanismsMolecular probes of the mechanism of cytochrome P450. Oxygen traps a substrate radical intermediateOxygen-independent decarbonylation of aldehydes by cyanobacterial aldehyde decarbonylase: a new reaction of diiron enzymes.X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative.Non-Redox Assisted Oxygen-Oxygen Bond Homolysis in Titanocene Alkylperoxide Complexes: [Cp(2)Ti(eta-OOBu)L], L = Cl, OTf, Br, OEt(2), Et(3)P.About oxygen, cytochrome p450 and titanium: learning from Ron Estabrook.Adaptive organic nanoparticles of a teflon-coated iron (III) porphyrin catalytically activate dioxygen for cyclohexene oxidationQM/MM study of the active species of the human cytochrome P450 3A4, and the influence thereof of the multiple substrate binding.Ipso-hydroxylation and subsequent fragmentation: a novel microbial strategy to eliminate sulfonamide antibiotics.Kinetic isotope effects in hydroxylation reactions effected by cytochrome P450 compounds I implicate multiple electrophilic oxidants for P450-catalyzed oxidations.Self-organized porphyrinic materialsVitamin C activation of the biosynthesis of epoxyeicosatrienoic acids.Enantioselective intramolecular C-H amination catalyzed by engineered cytochrome P450 enzymes in vitro and in vivo.Human CYPs involved in drug metabolism: structures, substrates and binding affinities.Functioning of drug-metabolizing microsomal cytochrome P450s: In silico probing of proteins suggests that the distal heme 'active site' pocket plays a relatively 'passive role' in some enzyme-substrate interactionsDesaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane.Functioning of Microsomal Cytochrome P450s: Murburn Concept Explains the Metabolism of Xenobiotics in Hepatocytes.Characterization of the microsomal cytochrome P450 2B4 O2 activation intermediates by cryoreduction and electron paramagnetic resonance.Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver.Single-turnover of nitric-oxide synthase in the presence of 4-amino-tetrahydrobiopterin: proposed role for tetrahydrobiopterin as a proton donor.Mechanism and structure-reactivity relationships for aromatic hydroxylation by cytochrome P450.Mononuclear Nonheme Iron(III)-Iodosylarene and High-Valent Iron-Oxo Complexes in Olefin Epoxidation Reactions.Superoxide-dependent oxidation of melatonin by myeloperoxidase.Mechanistic insight into peroxo-shunt formation of biomimetic models for compound II, their reactivity toward organic substrates, and the influence of N-methylimidazole axial ligation.Mechanistic Study of the Stereoselective Hydroxylation of [2-2 H1 ,3-2 H1 ]Butanes Catalyzed by Cytochrome P450 BM3 Variants.
P2860
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P2860
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@ast
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@en
type
label
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@ast
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@en
prefLabel
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@ast
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@en
P2093
P1476
Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations.
@en
P2093
Martin Newcomb
Minor J Coon
Paul F Hollenberg
P356
10.1016/S0003-9861(02)00445-9
P407
P577
2003-01-01T00:00:00Z