Role of common human TRIM5alpha variants in HIV-1 disease progression - Wikidata - awgldk - TriplyDB

Role of common human TRIM5alpha variants in HIV-1 disease progression

Role of common human TRIM5alpha variants in HIV-1 disease progression

http://www.wikidata.org/entity/Q35017461

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TRIM family proteins and their emerging roles in innate immunity TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies Cyclophilins and nucleoporins are required for infection mediated by capsids from circulating HIV-2 primary isolates.TRIM5 alpha drives SIVsmm evolution in rhesus macaques.The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection.Interpreting missense mutations in Human TRIM5alpha by computational methods Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species Stabilized human TRIM5α protects human T cells from HIV-1 infection.High systemic levels of interleukin-10, interleukin-22 and C-reactive protein in Indian patients are associated with low in vitro replication of HIV-1 subtype C viruses Host genetics influences on HIV type-1 disease.Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release TRIM5α restriction affects clinical outcome and disease progression in simian immunodeficiency virus-infected rhesus macaques Modulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.Vaccinomics: current findings, challenges and novel approaches for vaccine development Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha.Vaccinomics and a new paradigm for the development of preventive vaccines against viral infections.In silico analysis of functional single nucleotide polymorphisms in the human TRIM22 gene The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.APOBEC3G levels predict rates of progression to AIDS Host genes important to HIV replication and evolution.Host factors influencing susceptibility to HIV infection and AIDS progression.Genetic polymorphisms of Trim5a are associated with disease progression in acutely and chronically HIV-infected patients.Antiretroviral activity of ancestral TRIM5alpha.Host restriction factors in retroviral infection: promises in virus-host interaction.The control of viral infection by tripartite motif proteins and cyclophilin A.A naturally occurring single amino acid substitution in human TRIM5α linker region affects its anti-HIV type 1 activity and susceptibility to HIV type 1 infection.Special anniversary review: twenty-five years of human immunodeficiency virus research: successes and challenges.Pressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.Host genes associated with HIV/AIDS: advances in gene discovery Host Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic Approaches Previously Unidentified Single Nucleotide Polymorphisms in HIV/AIDS Cases Associate with Clinical Parameters and Disease Progression.TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.Recent insights into the mechanism and consequences of TRIM5α retroviral restriction.Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity.Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death.TRIM5 gene polymorphisms in HIV-1-infected patients and healthy controls from Northeastern Brazil.Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1.

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Role of common human TRIM5alpha variants in HIV-1 disease progression

http://www.wikidata.org/entity/Q35017461

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2006 nî lūn-bûn

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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Role of common human TRIM5alpha variants in HIV-1 disease progression

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Role of common human TRIM5alpha variants in HIV-1 disease progression

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Role of common human TRIM5alpha variants in HIV-1 disease progression

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Role of common human TRIM5alpha variants in HIV-1 disease progression

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Amalio Telenti

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Gabriela Bleiber

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Millàn Ortiz

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Raquel Martinez

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Valérie Goldschmidt

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P2860

The tripartite motif family identifies cell compartments.

TRIM family proteins: retroviral restriction and antiviral defence

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

Patterns of evolution of host proteins involved in retroviral pathogenesis.

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates

Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel.

Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction

Use of a combined ex vivo/in vivo population approach for screening of human genes involved in the human immunodeficiency virus type 1 life cycle for variants influencing disease progression

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10.1186/1742-4690-3-54

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3

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Swiss HIV Cohort Study

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2006-08-22T00:00:00Z

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6862072

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16925802

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1560158

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