The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.
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TRIM5α and Species Tropism of HIV/SIVImpact of TRIM5α in vivoNonhuman primate models for HIV/AIDS vaccine developmentUsing nonhuman primates to model HIV transmissionVaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replicationResistance to simian immunodeficiency virus low dose rectal challenge is associated with higher constitutive TRIM5α expression in PBMCTRIM5 alpha drives SIVsmm evolution in rhesus macaques.Phenotypic properties of transmitted founder HIV-1Expression of structural proteins in human female and male genital epithelia and implications for sexually transmitted infections.Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 vaRole of Human TRIM5α in Intrinsic Immunity.TRIM5 structure, HIV-1 capsid recognition, and innate immune signalingA trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challengeAssociation of MHC-I genotypes with disease progression in HIV/SIV infections.HIV transmission biology: translation for HIV prevention.HIV transmissionProtection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure.Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus VaccineHeterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock.A variant macaque-tropic human immunodeficiency virus type 1 is resistant to alpha interferon-induced restriction in pig-tailed macaque CD4+ T cellsSusceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques.TRIM5α Resistance Escape Mutations in the Capsid Are Transferable between Simian Immunodeficiency Virus Strains.Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV-1.Sensing of HIV-1 Infection in Tzm-bl Cells with Reconstituted Expression of STING.Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies: model parameter considerations and consequences.Tackling HIV and AIDS: contributions by non-human primate models.High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.Assessment of penile erection methods in rhesus macaques to model pharmacokinetics of antiretroviral drugs and penile infection with simian immunodeficiency virus.Sequential evolution and escape from neutralization of simian immunodeficiency virus SIVsmE660 clones in rhesus macaques.Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy.Development of a repeat-exposure penile SHIV infection model in macaques to evaluate biomedical preventions against HIV.
P2860
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P2860
The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@ast
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@en
type
label
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@ast
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@en
prefLabel
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@ast
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@en
P2093
P2860
P50
P356
P1433
P1476
The TRIM5 gene modulates penil ...... iency virus in rhesus monkeys.
@en
P2093
Adam P Buzby
Alan Dodson
Corinne Luedemann
James B Whitney
Jinrong Zhang
John Paul Todd
Laura M Brassard
Norman L Letvin
So-Yon Lim
P2860
P304
10389-10398
P356
10.1128/JVI.00854-11
P407
P577
2011-07-20T00:00:00Z