Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
about
A cluster of hematopoietic serine protease genes is found on the same chromosomal band as the human alpha/delta T-cell receptor locusA quarter century of granzymescDNA sequences of two inducible T-cell genesCAP37, a human neutrophil-derived chemotactic factor with monocyte specific activityPerforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of themCloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine proteasePurification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactionsThe isolation and sequence of a novel gene from a human functional T cell lineCloning CTL-Specific Genes (And Now for Something Completely Differential)Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genesPurification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytesSecretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populationsImpaired electroretinogram (ERG) response in apolipoprotein E-deficient miceStructure of a cytotoxic T-lymphocyte-specific gene shows a strong homology to fibrinogen beta and gamma chains.A new approach to understanding T cell development: the isolation and characterization of immature CD4-, CD8-, CD3- T cell cDNAs by subtraction cloning.Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytesMolecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytesCasein expression in cytotoxic T lymphocytes.Transgenic mice carrying the diphtheria toxin A chain gene under the control of the granzyme A promoter: expected depletion of cytotoxic cells and unexpected depletion of CD8 T cellsCloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets.Granzyme A activates another way to dieProduction of granulocyte/macrophage-colony-stimulating factor by human natural killer cells. Modulation by the p75 subunit of the interleukin 2 receptor and by the CD2 receptor.Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes.Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing.Cloning of cDNA for human granzyme 3.Isolation and initial characterization of multiple species of T-lymphocyte subset cDNA clones.Induction of synthesis of the cytolytic C9 (ninth component of complement)-related protein in human peripheral mononuclear cells by monoclonal antibody OKT3 or interleukin 2: correlation with cytotoxicity and lymphocyte phenotype.Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9.The action of leucyl-leucine methyl ester on cytotoxic lymphocytes requires uptake by a novel dipeptide-specific facilitated transport system and dipeptidyl peptidase I-mediated conversion to membranolytic products.Serine esterase and hemolytic activity in human cloned cytotoxic T lymphocytes.A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor.Isolation and sequence analysis of serine protease cDNAs from mouse cytolytic T lymphocytes.In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection.Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin AProtein tyrosine kinase p56-Lck regulates lymphocyte function-associated 1 adhesion molecule expression, granule exocytosis, and cytolytic effector function in a cloned T cell.Transcription of granzyme A and B genes is differentially regulated during lymphoid ontogeny.Human T cell specific proteinase (HuTSP) is encoded by the T cell and natural killer cell specific human Hanukah factor (HuHF) gene.Complexity of the primary genetic response to mitogenic activation of human T cells
P2860
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P2860
Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
description
1986 nî lūn-bûn
@nan
1986 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
@en
type
label
Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
@en
prefLabel
Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
@en
P356
P1433
P1476
Cloning of a cDNA for a T cell-specific serine protease from a cytotoxic T lymphocyte.
@en
P2093
Gershenfeld HK
Weissman IL
P304
P356
10.1126/SCIENCE.2422755
P407
P577
1986-05-01T00:00:00Z