Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia.
about
miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221Differential expression of placental glucocorticoid receptors and growth arrest-specific transcript 5 in term and preterm pregnancies: evidence for involvement of maternal stressExpression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells.Low dose of 2-deoxy-D-glucose kills acute lymphoblastic leukemia cells and reverses glucocorticoid resistance via N-linked glycosylation inhibition under normoxia.Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model.Bim polymorphisms: influence on function and response to treatment in children with acute lymphoblastic leukemia.Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia.RCAN1 is an important mediator of glucocorticoid-induced apoptosis in human leukemic cells.Transcript profiling and RNA interference as tools to identify small molecule mechanisms and therapeutic potential.Ginsenoside Rh1 Improves the Effect of Dexamethasone on Autoantibodies Production and Lymphoproliferation in MRL/lpr MiceTissue-selective therapy of cancer.Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.Glucocorticoid use in acute lymphoblastic leukaemiaHigh-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.Heat shock proteins and acute leukemias.MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.Gene set enrichment analysis unveils the mechanism for the phosphodiesterase 4B control of glucocorticoid response in B-cell lymphoma.Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Towards targeted therapy for infant acute lymphoblastic leukaemia.Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoidsExploring the molecular mechanisms of glucocorticoid receptor action from sensitivity to resistance.The pro-social neurohormone oxytocin reverses the actions of the stress hormone cortisol in human ovarian carcinoma cells in vitroProtein kinase A (PKA) isoform RIIbeta mediates the synergistic killing effect of cAMP and glucocorticoid in acute lymphoblastic leukemia cellsThe SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia.Long-term low level glucocorticoid exposure induces persistent repression in chromatin.NF-kappaB signaling, liver disease and hepatoprotective agents.Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics.Genomic approaches to small molecule discovery.NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia.Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations.Glucocorticoid sensitivity in health and disease.Steroid resistance in leukemia.Expression of 11beta-hydroxysteroid dehydrogenase 2 contributes to glucocorticoid resistance in lymphoblastic leukemia cells.A childhood acute lymphoblastic leukemia-specific lncRNA implicated in prednisolone resistance, cell proliferation, and migrationStress hormones promote growth of B16-F10 melanoma metastases: an interleukin 6- and glutathione-dependent mechanism.Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells.Aberrant microRNA-182 expression is associated with glucocorticoid resistance in lymphoblastic malignancies.Research resource: transcriptional response to glucocorticoids in childhood acute lymphoblastic leukemiaGX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy.
P2860
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P2860
Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Molecular determinants of gluc ...... acute lymphoblastic leukemia.
@en
type
label
Molecular determinants of gluc ...... acute lymphoblastic leukemia.
@en
prefLabel
Molecular determinants of gluc ...... acute lymphoblastic leukemia.
@en
P2093
P356
P1433
P1476
Molecular determinants of gluc ...... acute lymphoblastic leukemia.
@en
P2093
Meijerink JP
Tissing WJ
den Boer ML
P2888
P356
10.1038/SJ.LEU.2402733
P577
2003-01-01T00:00:00Z
P5875
P6179
1018838242