Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.
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Histone H3K27ac separates active from poised enhancers and predicts developmental stateEpigenetics of Peripheral B-Cell Differentiation and the Antibody ResponseThe Interplay between Chromatin and Transcription Factor Networks during B Cell Development: Who Pulls the Trigger First?AID targeting is dependent on RNA polymerase II pausing.Epigenetic control of immunityAnalysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locusEpigenetic regulation of antigen receptor gene rearrangementCTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination.Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.Three-dimensional architecture of the IgH locus facilitates class switch recombination.Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.Sequential activation and distinct functions for distal and proximal modules within the IgH 3' regulatory regionTwo forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus.Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctionsAID hits the jackpot when missing the target.Role of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition.Genomic Architecture may Influence Recurrent Chromosomal Translocation Frequency in the Igh Locus.Design principles of adaptive immune systems.Old questions, new tools: does next-generation sequencing hold the key to unraveling intestinal B-cell responses?Seeking sense of antisense switch transcripts.BTK Signaling in B Cell Differentiation and Autoimmunity.Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.Epigenetic Regulation in Amyloid Precursor Protein with Genomic Rearrangements and the Lesch-Nyhan Syndrome.4C-ing the Igh Landscape.CTCF-binding elements mediate control of V(D)J recombinationAllelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells.Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain Loci.The contraction of time and space in remote chromosomal interactions.Epigenetic modifications of the VH region after DJH recombination in Pro-B cells.The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination
P2860
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P2860
Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Cis-regulatory elements and ep ...... arrangements of the IgH locus.
@en
type
label
Cis-regulatory elements and ep ...... arrangements of the IgH locus.
@en
prefLabel
Cis-regulatory elements and ep ...... arrangements of the IgH locus.
@en
P2860
P1476
Cis-regulatory elements and ep ...... arrangements of the IgH locus.
@en
P2093
Frederick W Alt
Thomas Perlot
P2860
P356
10.1016/S0065-2776(08)00601-9
P577
2008-01-01T00:00:00Z