An unliganded thyroid hormone receptor causes severe neurological dysfunction - Wikidata - awgldk - TriplyDB

An unliganded thyroid hormone receptor causes severe neurological dysfunction

An unliganded thyroid hormone receptor causes severe neurological dysfunction

http://www.wikidata.org/entity/Q35050227

about

Molecular aspects of thyroid hormone actions Clinical Consequences of Mutations in Thyroid Hormone Receptor-α1 Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases Homozygous thyroid hormone receptor β-gene mutations in resistance to thyroid hormone: three new cases and review of the literature.Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormone Behavioral inhibition and impaired spatial learning and memory in hypothyroid mice lacking thyroid hormone receptor alpha Influence of maternal thyroid hormones during gestation on fetal brain development.Complete activation of thyroid hormone receptor β by T3 is essential for normal cochlear function and morphology in mice.A dominant-negative thyroid hormone receptor blocks amphibian metamorphosis by retaining corepressors at target genes.Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.A bimodal influence of thyroid hormone on cerebellum oligodendrocyte differentiation.Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells.A targeted dominant negative mutation of the thyroid hormone alpha 1 receptor causes increased mortality, infertility, and dwarfism in mice.Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor alpha1 can be ameliorated by T3 treatment.Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1 Genome-wide search reveals the existence of a limited number of thyroid hormone receptor alpha target genes in cerebellar neurons.Nitric oxide contributes to learning and memory deficits observed in hypothyroid rats during neonatal and juvenile growth.Function of RARalpha during the maturation of neutrophils.Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain.Crosstalk between thyroid hormone receptor and liver X receptor in the regulation of selective Alzheimer's disease indicator-1 gene expression.Identification of thyroid hormone receptor binding sites in developing mouse cerebellum.Thyroid hormone action in cerebellum and cerebral cortex development.Active repression by unliganded retinoid receptors in development: less is sometimes more Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).Activation of the RhoB signaling pathway by thyroid hormone receptor β in thyroid cancer cells Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation.Profound morphological and functional changes of rodent Purkinje cells between the first and the second postnatal weeks: a metamorphosis?Thyroid hormone receptors and resistance to thyroid hormone disorders.Age-Related Hearing Loss and Degeneration of Cochlear Hair Cells in Mice Lacking Thyroid Hormone Receptor β1 Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells.Dissecting the role of retinoic acid receptor isoforms in the CD8 response to infection.Cerebellar abnormalities in mice lacking type 3 deiodinase and partial reversal of phenotype by deletion of thyroid hormone receptor α1 General background on the hypothalamic-pituitary-thyroid (HPT) axis.Role of Thyroid Hormones in Skeletal Development and Bone Maintenance.Multigenic control of thyroid hormone functions in the nervous system.Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α Thyroid hormones, learning and memory.Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice.

P2860

Q22306217-784CB4E3-120B-46FF-AE09-E3FC98F9DCCD Q26830635-E93EC925-29BE-4741-8810-267BF3660B07 Q27025212-8F3FE13F-FC95-4D4A-A2A6-3696676DA4DB Q27693183-F6778AE9-511F-46C5-B5E4-BA2B0FB87CD0 Q28303035-D122EA72-841F-4416-ABDE-3D8E118F8952 Q28588135-389F0DCF-93C4-42C7-85D2-9B005C423605 Q30252084-2DC7E7A9-3C49-48AF-BF0A-7B6D5887E48D Q30451822-2027223E-CD18-49FD-85D5-23D80032E982 Q30452390-42D196EE-80A7-4DEF-848A-BC1521AB9AB0 Q30531151-177D2292-0C43-4CB9-A942-C795C2167899 Q33636657-14C8F877-9E3C-4801-BF01-5F568B500AB3 Q33914645-E96C949C-3599-4A97-A267-1CA372F32B40 Q33935268-C8C6BDC8-AF0A-4F54-BAA9-03F342CD4D2F Q33952931-27F81BAA-7F13-4D0B-880D-C07926C979F8 Q34009147-07AB3938-D51F-4375-B22C-2F782BC0D639 Q34015126-D0305F5A-7F21-452F-8B53-537EA609B524 Q34149746-94C16745-ADFD-47D1-A7A2-449169187B66 Q34268981-D88C57A0-5233-4D89-81BC-EBB4EC86F991 Q34394066-F0CF4B65-911C-44FF-BB09-119671D06169 Q34435515-2C4C678A-406A-4D5D-89A8-8071CD370E97 Q34526557-CEB95A8F-42AC-417F-92EB-83C961081E2A Q34566203-F9246390-A9CE-43AA-A2CF-B3FB36981E74 Q34735969-5EB4F334-750E-4086-B5E2-20591AB0CCC4 Q35098663-34B45BF4-8C3A-4798-806C-EF60E71FBCE8 Q35116527-D660F259-F146-4ECD-A3BA-929A41FDDCAF Q35408730-C346C61B-B631-4412-99DF-788A9FC9E5E5 Q35535645-6BC0E60F-3B9F-4BB4-B9AB-4C32E68A8806 Q35639785-6F70E5E2-0FE4-4975-B36B-49F691E6F4B4 Q35882713-314CC2A7-2CF9-4732-B1D6-14AC1D7ABE47 Q36083186-7B8304AB-A853-4492-9BB8-64AD5BBB69BC Q36107528-1946F7D5-39B1-4171-96B8-AB965C505754 Q36213032-84FAEACB-8C73-4613-9800-B6C6E3C86194 Q36288127-4E843398-AB67-4F41-BAC0-06E3D189A049 Q36486112-865C3998-0B19-47AC-AD65-5057414A2EB7 Q36761575-04EBA844-A306-4A52-BFA9-7C9F1AECC98B Q36773018-EC9121C5-1174-45C6-AB12-1CB1C3F87520 Q36793594-78B36A22-8737-4EB4-BC5E-02130EAF9090 Q36835486-168A8ECC-A711-4074-883A-126C61A8B6C3 Q36837331-A1AC7827-AF8F-4E08-AED2-80D09CFE093E Q37125997-98E82804-BA51-4B0C-9847-DC98E25162ED

P2860

An unliganded thyroid hormone receptor causes severe neurological dysfunction

http://www.wikidata.org/entity/Q35050227

description

2001 nî lūn-bûn

@nan

2001 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի մարտին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@ast

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@en

type

label

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@ast

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@en

prefLabel

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@ast

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@en

P1433

Q35050227-11C2F8A9-8D8C-4E42-9A97-2BAC570A8A82

P1476

Q35050227-1D1AA89B-ECFB-4E62-92B3-CE1C008A8070

P2093

Q35050227-0F5FA702-A4AA-49B4-9973-D09D3A325B5E

Q35050227-473BC521-FF37-4EC0-B3AF-7DD50145B116

Q35050227-49B1D959-F776-4E58-A93E-6E24B014BFB6

Q35050227-631641CC-81AF-4A52-AB7C-906DAEC5D5F4

Q35050227-7CA84C15-C700-41DB-880D-C5ACA94C4943

Q35050227-F5EC69E9-10EE-4313-AD28-2F31292A4D92

Q35050227-F7FF675A-0EE5-4448-9048-A8EC873AD10A

P2860

Q35050227-063DB82F-93FA-4E49-8CDC-00490DF6F92E

Q35050227-06A10E0A-851F-4C01-86D0-F0542896CCC2

Q35050227-104F8652-907D-4252-8CCA-2CF3F2CBBB18

Q35050227-15A978B0-3BF8-474C-AC9D-2BD2967F7787

Q35050227-27E0046B-502E-47A3-BDF3-BF0CFFC11A47

Q35050227-2C697728-EF56-46E3-BFD1-003A55EA2668

Q35050227-3BA7EAEB-44BD-4011-8BC1-2C369FFAB87A

Q35050227-3C7F144F-0DB3-4F1F-8DCB-19242EFBEF59

Q35050227-3F334B7F-0017-4B59-B2E4-FC8E54C47D2F

Q35050227-4281EAAC-F208-4A49-B55E-546AFCDC5E0E

P304

Q35050227-DDD0B681-4E5E-464B-AFC4-4E38F6A1EB10

P31

Q35050227-96B761A2-EDB7-4658-B5CA-1D8D353503B9

P356

Q35050227-91905521-5B21-409A-9CA8-751BAF85061A

P407

Q35050227-21E7BDE0-5AE6-4ED5-AF58-0487B97CC683

P433

Q35050227-D3D2798C-4962-48CA-86B2-39C4DDBC954F

P478

Q35050227-1AF4D5DC-F587-47E3-BCB8-C1937D607CBD

P50

Q35050227-DC1A3D40-AFAD-4F85-84DD-61A13F509119

P577

Q35050227-B9C20BC9-DC37-43CC-BA35-2F6E6F0E5253

P5875

Q35050227-B46B1E92-93EF-44C6-BFD8-2F9592AD502B

P698

Q35050227-56CE345E-DAC1-4CF3-B1D2-B32D3CA4152F

P932

Q35050227-198214A0-1A59-418A-8980-D60DE5FF36A2

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

An unliganded thyroid hormone receptor causes severe neurological dysfunction

@en

P2093

C E Lee

http://www.w3.org/2001/XMLSchema#string

F E Wondisford

http://www.w3.org/2001/XMLSchema#string

F H Curty

http://www.w3.org/2001/XMLSchema#string

J K Elmquist

http://www.w3.org/2001/XMLSchema#string

K Hashimoto

http://www.w3.org/2001/XMLSchema#string

P P Borges

http://www.w3.org/2001/XMLSchema#string

R N Cohen

http://www.w3.org/2001/XMLSchema#string

P2860

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Divergent roles for thyroid hormone receptor beta isoforms in the endocrine axis and auditory system.

A transcriptional co-repressor that interacts with nuclear hormone receptors

A homozygous deletion in the c-erbA beta thyroid hormone receptor gene in a patient with generalized thyroid hormone resistance: isolation and characterization of the mutant receptor

Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development

Thyroid hormone receptor beta is essential for development of auditory function

Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production

Essential role for TrkB receptors in hippocampus-mediated learning

P304

3998-4003

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.051454698

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

98

http://www.w3.org/2001/XMLSchema#string

P50

P577

2001-03-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12059554

http://www.w3.org/2001/XMLSchema#string

P698

11274423

http://www.w3.org/2001/XMLSchema#string

P932

31168

http://www.w3.org/2001/XMLSchema#string