Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation.
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Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolismSynthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemiaLiver X receptors at the intersection of lipid metabolism and atherogenesisThe liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXRLiver X Receptors Link Lipid Metabolism and Inflammation.Transcriptome profiling of the feeding-to-fasting transition in chicken liver.Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.Discovering networks of perturbed biological processes in hepatocyte culturesMolecular pathways in non-alcoholic fatty liver disease.Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.Group X secretory phospholipase A2 negatively regulates adipogenesis in murine modelsA functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses.Role of stearoyl-coenzyme A desaturase in regulating lipid metabolismLoss of stearoyl-CoA desaturase activity leads to free cholesterol synthesis through increased Xbp-1 splicing.MicroRNA hsa-miR-613 targets the human LXRα gene and mediates a feedback loop of LXRα autoregulation.Biochemical and physiological function of stearoyl-CoA desaturase.Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity.Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discoverySCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice.Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cellsApolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPARγ and Fatty Acid Uptake.Maternal high-fat-diet programs rat offspring liver fatty acid metabolism.Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sitesHepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions.Distinct regulation of stearoyl-CoA desaturase 1 gene expression by cis and trans C18:1 fatty acids in human aortic smooth muscle cells.Repression of endometrial tumor growth by targeting SREBP1 and lipogenesisLoss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cellsSterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob MiceContribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice.Reproduction, fat metabolism, and life span: what is the connection?Freshwater Clam Extract Ameliorates Triglyceride and Cholesterol Metabolism through the Expression of Genes Involved in Hepatic Lipogenesis and Cholesterol Degradation in RatsHepatic and plasma sex differences in saturated and monounsaturated fatty acids are associated with differences in expression of elongase 6, but not stearoyl-CoA desaturase in Sprague-Dawley rats.Role of ChREBP in hepatic steatosis and insulin resistance.Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed miceDyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase.Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2.Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice.Fatty acid desaturation index correlates with body mass and adiposity indices of obesity in Wistar NIN obese mutant rat strains WNIN/Ob and WNIN/GR-Ob.Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis.Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis
P2860
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P2860
Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@ast
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@en
type
label
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@ast
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@en
prefLabel
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@ast
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@en
P2093
P2860
P356
P1476
Stearoyl-coenzyme A desaturase ...... y liver X receptor activation.
@en
P2093
James M Ntambi
Makoto Miyazaki
Weng Chi Man
P2860
P304
P356
10.1128/MCB.00077-06
P407
P577
2006-09-01T00:00:00Z