Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.
about
Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptorsDynamic Regulation of N-Methyl-d-aspartate (NMDA) and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors by Posttranslational ModificationsANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit LocalizationRegulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neuronsRing finger protein 34 (RNF34) interacts with and promotes γ-aminobutyric acid type-A receptor degradation via ubiquitination of the γ2 subunitThe Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.The NMDA receptor as a target for cognitive enhancementPost-translational modification biology of glutamate receptors and drug addictionThe deubiquitinating enzyme USP-46 negatively regulates the degradation of glutamate receptors to control their abundance in the ventral nerve cord of Caenorhabditis elegans.New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.Ubiquitination in postsynaptic function and plasticityThe E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation.Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity.UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel EndocytosisDephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP.Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity.The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafishGene coexpression networks in human brain identify epigenetic modifications in alcohol dependenceUbiquitination of neurotransmitter receptors and postsynaptic scaffolding proteinsNMDA hypofunction as a convergence point for progression and symptoms of schizophreniaRegulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity.Lys-63-linked Ubiquitination of γ-Aminobutyric Acid (GABA), Type B1, at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation.Calpain and the glutamatergic synapseUbiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins.Role of the ubiquitin-proteasome system in nervous system function and disease: using C. elegans as a dissecting tool.Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseases.Ubiquitin pathways in neurodegenerative disease.Perturbed proteostasis in autism spectrum disorders.Proteolysis, synaptic plasticity and memory.Ubiquitination and the Regulation of Membrane Proteins.Gene expression profiling in the human alcoholic brain.Recent insights on principles of synaptic protein degradationThe effects of proteasomal inhibition on synaptic proteostasis.Toponomics analysis of functional interactions of the ubiquitin ligase PAM (Protein Associated with Myc) during spinal nociceptive processing.Protein Modifications with Ubiquitin as Response to Cerebral Ischemia-Reperfusion Injury.
P2860
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P2860
Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.
@ast
Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.
@en
type
label
Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.
@ast
Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.
@en
prefLabel
Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.
@ast
Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.
@en
P2093
P2860
P356
P1476
Mind bomb-2 is an E3 ligase th ...... osphorylation-dependent manner
@en
P2093
Khanhky Phamluong
Rachel Jurd
Stuart L Gibb
Viktor Kharazia
P2860
P304
P356
10.1074/JBC.M705580200
P407
P577
2007-10-25T00:00:00Z