Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner. - Wikidata - awgldk - TriplyDB

Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.

Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.

http://www.wikidata.org/entity/Q35071725

about

Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors Dynamic Regulation of N-Methyl-d-aspartate (NMDA) and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors by Posttranslational Modifications ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons Ring finger protein 34 (RNF34) interacts with and promotes γ-aminobutyric acid type-A receptor degradation via ubiquitination of the γ2 subunit The Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.The NMDA receptor as a target for cognitive enhancement Post-translational modification biology of glutamate receptors and drug addiction The deubiquitinating enzyme USP-46 negatively regulates the degradation of glutamate receptors to control their abundance in the ventral nerve cord of Caenorhabditis elegans.New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.Ubiquitination in postsynaptic function and plasticity The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation.Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity.UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis Dephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP.Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity.The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence Ubiquitination of neurotransmitter receptors and postsynaptic scaffolding proteins NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity.Lys-63-linked Ubiquitination of γ-Aminobutyric Acid (GABA), Type B1, at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation.Calpain and the glutamatergic synapse Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins.Role of the ubiquitin-proteasome system in nervous system function and disease: using C. elegans as a dissecting tool.Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseases.Ubiquitin pathways in neurodegenerative disease.Perturbed proteostasis in autism spectrum disorders.Proteolysis, synaptic plasticity and memory.Ubiquitination and the Regulation of Membrane Proteins.Gene expression profiling in the human alcoholic brain.Recent insights on principles of synaptic protein degradation The effects of proteasomal inhibition on synaptic proteostasis.Toponomics analysis of functional interactions of the ubiquitin ligase PAM (Protein Associated with Myc) during spinal nociceptive processing.Protein Modifications with Ubiquitin as Response to Cerebral Ischemia-Reperfusion Injury.

P2860

Q26777280-A2D793D8-FCD5-4BB7-8F74-B3C22B1338B7 Q28080971-2595DE23-B67A-42CA-9315-FC40BB21A037 Q28511930-A336B69D-FFCA-4376-A2AB-90FD9E5D13B0 Q28577634-C4852249-580A-4FBD-ABD0-58172E9DE6EB Q28578977-FEE4D2E5-2C02-4742-8DEE-DAA219F54097 Q33361879-9D6227A3-9B5E-4E41-B6A1-A5A4EA8E638E Q34288139-10006667-79A1-40C0-B129-E90BAE3BB8CE Q34706306-A65B605B-8BFD-43B4-B19F-46E7E328702C Q34886654-F499E73C-046E-4BD7-913C-485C79C15A59 Q35143169-8F3375AE-CF13-4A5F-A0BB-097CD67E8A69 Q35186220-FAB4418F-A6DC-4636-93C3-498BA2DB67B0 Q35423381-6BE18416-A6AB-4661-BB71-951926551C72 Q35423787-7078416D-D1A9-47C5-9347-CF6ECD880A63 Q35904353-9D00597D-6E5F-4328-97E8-C1792EBC30E5 Q36129932-E9698049-18CF-4A80-B724-EDA9C2DAB534 Q36260739-08F4F810-BF47-4C76-9E08-8EB63B851CBE Q36421459-096E5226-0095-4132-A708-D4961A0F7169 Q36506714-E7A772FB-F1AC-412F-9A89-1B9965702CA8 Q36587882-8EAB53DA-5061-4D60-9C3B-BB9A865EF609 Q36616412-657898D2-6FA6-45B7-A34B-F2E3838FE2B5 Q36718684-55396762-D094-446A-8355-C0472F436BEA Q36990383-E1BD33DA-011E-457F-9F16-87D3DE4FBD57 Q37361506-54BD29E9-4D0C-46DE-83EB-FF4EDFDB86D9 Q37502232-58A6D2EE-5E87-4DC9-AEAE-1CC5E7B0E3F6 Q37925180-E8C4D083-40ED-443F-978D-A56E857F8DF4 Q37989861-1812F686-C562-46D8-B711-140F9DA9B85E Q38044699-71B15412-4ECC-467F-A96D-8D6CA6409A7E Q38234883-8BCE6745-DC2A-4352-9D9F-821E3C205284 Q38882773-1F2EBEFF-C0E6-4C06-AB69-094F4F226863 Q38950862-F02E2848-2314-4E9C-8CE4-926EA7116143 Q39033646-422E4CEF-9C24-4C42-AC40-5DBA6E929E8F Q39158615-CFF6882A-38F4-42C4-B900-27AF5986E7D1 Q39377253-D88B0DD6-16D8-4807-BB1E-350210465484 Q42146983-5C4C54B2-D151-4EB3-90BA-6EB7411BAE00 Q46407306-C8AC54E1-0545-4518-9AF3-BE959A90FF0E Q47903181-E43FAB70-3E5A-4DCE-98EC-9C972BE4F009

P2860

Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.

http://www.wikidata.org/entity/Q35071725

description

2007 nî lūn-bûn

@nan

2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.

@ast

Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.

@en

type

label

Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.

@ast

Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.

@en

prefLabel

Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.

@ast

Mind bomb-2 is an E3 ligase th ...... sphorylation-dependent manner.

@en

P1433

Q35071725-5943E6F0-ACBA-4ACA-8CED-32B3ED796DED

P1476

Q35071725-ECC80E38-37C5-4E91-AAD7-EE4B26C21CC0

P2093

Q35071725-052D770B-DC8F-46BA-84AB-FB964FE1D7CA

Q35071725-66AB4597-9ED6-4B7B-9D2B-A48415324E89

Q35071725-826BD256-2642-45C2-99D9-73B3186B4ABB

Q35071725-A5DBB418-7E30-40CE-B149-A0E2048BF842

Q35071725-C2B03402-2736-488B-A27F-763995D76C9F

Q35071725-D04539A5-E41F-4FC2-A881-58A00BBE703C

P2860

Q35071725-07B96B6E-DFD3-4A90-B5E8-41274C5484CC

Q35071725-0F67269C-DAF5-4759-8892-7C15632BD774

Q35071725-21172FBB-C7A2-4012-B9D8-19354D2B0DEF

Q35071725-262CE16A-C148-4BDE-9467-C86136FA2A48

Q35071725-2E0565E1-0C6F-4DFB-8B95-9D8926728808

Q35071725-2FC4CF85-A7DF-4FF6-94EF-B85B07365AE4

Q35071725-32133B00-AB66-4A1E-B288-FDA411B53FD3

Q35071725-3B7B53EE-7817-4BBF-936C-1BBAB397BA80

Q35071725-3BDB1528-608F-42E6-BE4E-92CFD4174D03

Q35071725-40BB81FA-A99A-466A-823A-05110C18F4C2

P304

Q35071725-DD4B5F58-6AE1-40AC-9B04-B3F46CB7B74B

P31

Q35071725-E8E15ED5-ABCD-44FD-8114-CC62C2FD8E4A

P356

Q35071725-46B5B95C-E913-4815-BCB9-5E9AAE46F054

P407

Q35071725-781DDA99-6FB4-4CE2-99A5-75A74855F305

P433

Q35071725-DBB74B14-FFCF-4B15-96F2-E22C06199997

P478

Q35071725-7B5E1476-1CFC-4C6A-8730-2E168714E19B

P50

Q35071725-1248D7A8-77FF-4604-B10E-03B43C885052

Q35071725-9DA0956F-63A5-417A-8BB8-9523F2DAB09D

P577

Q35071725-005F211A-0FD6-40C3-9D34-F362761DBCDB

P698

Q35071725-7E31E15E-40F5-4098-9A91-F56902C379F2

P921

Q35071725-4CA2C2AE-A54C-4AA1-9E73-5DB9189243A6

Q35071725-C12DE699-4CD4-4AAA-9020-2498C841C927

P932

Q35071725-65E1EEEF-A52B-4162-8A3C-2361024BFD2D

P356

P1433

Journal of Biological Chemistry

P1476

Mind bomb-2 is an E3 ligase th ...... osphorylation-dependent manner

@en

P2093

Dorit Ron

http://www.w3.org/2001/XMLSchema#string

Ken Luong

http://www.w3.org/2001/XMLSchema#string

Khanhky Phamluong

http://www.w3.org/2001/XMLSchema#string

Rachel Jurd

http://www.w3.org/2001/XMLSchema#string

Stuart L Gibb

http://www.w3.org/2001/XMLSchema#string

Viktor Kharazia

http://www.w3.org/2001/XMLSchema#string

P2860

Converging Evidence of NMDA Receptor Hypofunction in the Pathophysiology of Schizophrenia

NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1

Mechanisms underlying ubiquitination

Getting started with yeast

Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1

GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1

Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand

Activity-dependent dynamics and sequestration of proteasomes in dendritic spines

Localization of the scaffolding protein RACK1 in the developing and adult mouse brain

Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function

P304

301-310

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M705580200

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

283

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-10-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17962190

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

protein ubiquitination

P932

3124443

http://www.w3.org/2001/XMLSchema#string