Multiple roles for the yeast SUB2/yUAP56 gene in splicing - Wikidata - awgldk - TriplyDB

Multiple roles for the yeast SUB2/yUAP56 gene in splicing

Multiple roles for the yeast SUB2/yUAP56 gene in splicing

http://www.wikidata.org/entity/Q35076347

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TREX is a conserved complex coupling transcription with messenger RNA export Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56 Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex.RNA helicases in splicing The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.A new connection of mRNP biogenesis and export with transcription-coupled repair Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56 The splicing ATPase prp43p is a component of multiple preribosomal particles.Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex.Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p.A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly The ATP requirement for U2 snRNP addition is linked to the pre-mRNA region 5' to the branch site.Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP 5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly.In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants Crystal structure of the human ATP-dependent splicing and export factor UAP56.ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA.Invariant U2 snRNA nucleotides form a stem loop to recognize the intron early in splicing.Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast Expression of the essential mRNA export factor Yra1p is autoregulated by a splicing-dependent mechanism.UAP56 levels affect viability and mRNA export in Caenorhabditis elegans.DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps.Role of transcription in plasmid maintenance in the hpr1Delta mutant of Saccharomyces cerevisiae Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly.Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase.The solution structure of REF2-I reveals interdomain interactions and regions involved in binding mRNA export factors and RNA.Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs.Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1p Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.UAP56 is a conserved crucial component of a divergent mRNA export pathway in Toxoplasma gondii An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis Definition of global and transcript-specific mRNA export pathways in metazoans.

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

http://www.wikidata.org/entity/Q35076347

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2001 nî lūn-bûn

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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2001 թվականի հունվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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Genes & Development

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

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P2093

Boulay J

http://www.w3.org/2001/XMLSchema#string

Graziani N

http://www.w3.org/2001/XMLSchema#string

Libri D

http://www.w3.org/2001/XMLSchema#string

Saguez C

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P2860

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2

Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly.

A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.

Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection.

In vitro studies of the Prp9.Prp11.Prp21 complex indicate a pathway for U2 small nuclear ribonucleoprotein activation.

Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle

The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA.

Mechanical devices of the spliceosome: motors, clocks, springs, and things.

Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families.

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36-41

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10.1101/GAD.852101

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1

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15

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2001-01-01T00:00:00Z

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11156603

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312604

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