Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling - Wikidata - awgldk - TriplyDB

Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling

Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling

http://www.wikidata.org/entity/Q35077552

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Highlights on distinctive structural and functional properties of HTLV Tax proteins NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?Regulation of NF-κB by ubiquitination Dysregulation of ubiquitin ligases in cancer HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains Deubiquitinating enzymes as promising drug targets for infectious diseases.An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation.HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation Systematic analysis of the physiological importance of deubiquitinating enzymes.HERC2-USP20 axis regulates DNA damage checkpoint through Claspin.Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling.Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.Deubiquitinases in cancer.Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms.Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.TRAF molecules in cell signaling and in human diseases TRIM38 inhibits TNFα- and IL-1β-triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3.Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells.Multifaceted roles of TRIM38 in innate immune and inflammatory responses.Molecular hallmarks of adult T cell leukemia.Human T-lymphotropic virus proteins and post-translational modification pathways Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients.Manipulation of viral infection by deubiquitinating enzymes: new players in host-virus interactions.1H, 13C and 15N backbone and side-chain resonance assignments of the ZnF-UBP domain of USP20/VDU2.Regulation of inflammation by β-arrestins: Not just receptor tales.Is there a role for ubiquitin or SUMO in human T-cell leukemia virus type 2 Tax-induced NF-κB activation?USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.New approaches to the inhibition of replication of viral pathogens.Conference highlights of the 15th International Conference on Human Retrovirology: HTLV and related retroviruses, 4-8 June 2011, Leuven, Gembloux, Belgium.NLRP11 attenuates Toll-like receptor signalling by targeting TRAF6 for degradation via the ubiquitin ligase RNF19A.Downregulation of USP4 Promotes Activation of Microglia and Subsequent Neuronal Inflammation in Rat Spinal Cord After Injury.Identification of genes associated with susceptibility to Mycobacterium avium ssp. paratuberculosis (Map) tissue infection in Holstein cattle using gene set enrichment analysis-SNP.Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways

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Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling

http://www.wikidata.org/entity/Q35077552

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

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Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

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type

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Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

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Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

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Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

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Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

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P1433

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Journal of Virology

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Ubiquitin-specific peptidase 2 ...... y regulate NF-kappaB signaling

@en

P2093

Kuan-Teh Jeang

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Xiongbin Lu

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P2860

The HTLV-1 Tax interactome

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization

VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.

Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2

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6212-6219

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scholarly article

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10.1128/JVI.00079-11

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13

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85

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Jun-ichirou Yasunaga

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2011-04-27T00:00:00Z

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21525354

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3126525

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